ArticleMenopause (New York, N.Y.)2011
Trends in menopausal hormone therapy use of US office-based physicians, 2000-2009.
Article in Menopause (New York, N.Y.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Improving vasomotor symptoms; psychological symptoms; and health-related quality of life in peri- or post-menopausal women through yoga: An umbrella systematic review and meta-analysis.Complementary therapies in medicine · 2017Pooled it
- Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer's disease.Epidemiologic reviews · 2014Pooled it
- Long-term cognitive effects of menopausal hormone therapy: Findings from the KEEPS Continuation Study.PLoS medicine · 2024Trial
- Sexual activity and vaginal symptoms in the postintervention phase of the Women's Health Initiative Hormone Therapy Trials.Menopause (New York, N.Y.) · 2018Trial
- TX-004HR vaginal estradiol has negligible to very low systemic absorption of estradiol.Menopause (New York, N.Y.) · 2017Trial
- Breast Cancer After Use of Estrogen Plus Progestin and Estrogen Alone: Analyses of Data From 2 Women's Health Initiative Randomized Clinical Trials.JAMA oncology · 2015Trial
- Pilot study of integral yoga for menopausal hot flashes.Menopause (New York, N.Y.) · 2014Trial
- The mortality toll of estrogen avoidance: an analysis of excess deaths among hysterectomized women aged 50 to 59 years.American journal of public health · 2013Trial
- Impact of dose, frequency of administration, and equol production on efficacy of isoflavones for menopausal hot flashes: a pilot randomized trial.Menopause (New York, N.Y.) · 2013Trial
- Design and methods of a multi-site, multi-behavioral treatment trial for menopausal symptoms: the MsFLASH experience.Contemporary clinical trials · 2013Trial
- Coronary heart disease events in the Women's Health Initiative hormone trials: effect modification by metabolic syndrome: a nested case-control study within the Women's Health Initiative randomized clinical trials.Menopause (New York, N.Y.) · 2013Trial
- Menopausal hormone therapy and risks of melanoma and nonmelanoma skin cancers: women's health initiative randomized trials.Journal of the National Cancer Institute · 2011Trial
- Ambient particulate matter air pollution and venous thromboembolism in the Women's Health Initiative Hormone Therapy trials.Environmental health perspectives · 2011Trial
- Trends in estrogen replacement therapy use among younger gynecologic cancer survivors, 2013-2021.Gynecologic oncology reports · 2026Article
- Vaginal Estrogen Utilization Among Medicare Beneficiaries With Genitourinary Syndrome of Menopause.JAMA network open · 2025Article
- Menopausal Hormone Therapy Use Among Postmenopausal Women.JAMA health forum · 2024Article
- A Simple Mathematical Model Demonstrates the Potential for Cell-Based Hormone Therapy to Address Dysregulation of the Hypothalamus-Pituitary-Ovary Axis in Females with Loss of Ovarian Function.Annals of biomedical engineering · 2024Article
- Benign Breast Disease and Breast Cancer Risk in the Percutaneous Biopsy Era.JAMA surgery · 2024Article
- Health-Seeking Behaviors and Treatments Received for Menopause Symptoms: A Questionnaire Survey among Midlife Women Attending Primary Healthcare Clinics in Malaysia.Journal of menopausal medicine · 2023Article
- Menopausal hormone therapy and risk of cardiovascular events in women with prediabetes or type 2 diabetes: A pooled analysis of 2917 postmenopausal women.Atherosclerosis · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveThe aim of this study was to evaluate recent trends and the adoption of practice recommendations for menopausal hormone therapy (MHT) use from 2001 to 2009 by formulation, dose, woman's age, and characteristics of physicians reporting MHT visits.
methodsThe IMS Health (Plymouth Meeting PA) National Disease and Therapeutic Index physician survey data from 2001 to 2009 were analyzed for visits in which MHT use was reported by US office-based physicians. Estimated national volume of visits for which MHT use was reported.
resultsMHT use declined each year since 2002. Systemic MHT use fell from 16.3 million (M) visits in 2001 to 6.1 M visits in 2009. Declines were greatest for women 60 years or older (64%) but were also substantial for women younger than 50 years (59%) and women 50 to 59 years old (60%). Women 60 years or older accounted for 37% of MHT use. Lower dose product use increased modestly, from 0.7 M (2001) to 1.3 M (2009), as did vaginal MHT use, from 1.8 M (2001) to 2.4 M (2009). Declines in continuing systemic MHT use (65%) were greater than for newly initiated MHT use (51%). Compared with other physicians, obstetrician/gynecologists changed their practices less, thereby increasing their overall share of total MHT visits from 72% (2001) to 82% (2009).
conclusionsTotal MHT use has steadily declined. Increased use of lower dose and vaginal products reflects clinical recommendations. Uptake of these products, however, has been modest, and substantial use of MHT continues in older women.
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Registered trials
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