Evidence map›Paper›PMID 21127353›Full record

ArticleAlcohol and alcoholism (Oxford, Oxfordshire)

Response inhibition impairments predict alcohol-induced sedation.

Erin E Shannon, Elizabeth R Staniforth, Juliette McNamara, Kimberly A Bernosky-Smith, Anthony Liguori

Abstract read
In one paragraph

Article in Alcohol and alcoholism (Oxford, Oxfordshire). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
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  9. Anxiety, sedation, and simulated driving in binge drinkers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erin E ShannonDepartment of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.
Elizabeth R Staniforth
Juliette McNamara
Kimberly A Bernosky-Smith
Anthony Liguori

Funding

MULTI-DISCIPLINARY TRAINING IN THE BIOLOGY OF ALCOHOLISMT32AA007565 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BRIAN A MCCOOL · 1994 to 2026
$10.1M
Translational Centerfor the Neurobehaviral Study of AlcoholP01AA017056 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WEINER, JEFFREY L. · 2008 to 2012
$2.0M
NIAAA NIH HHS AA017056NIAAA NIH HHS AA07565NIAAA NIH HHS T32 AA007565
6 · The paper itself

Abstract

aimsThe aim of this study was to probe the relationship between the subjective effects of alcohol and impulsive behavior in social drinkers.

methodsFifty social drinkers performed a response-inhibition task before consuming alcohol. A 0.8-g/kg dose of alcohol was administered in a binge-like fashion (0.2 g/kg every 30 min) to the participants over a 2-h time period. Participants then completed questionnaires measuring stimulation, sedation and mood following consumption of alcohol. Linear regression analyses were performed by examining the relationship between performance on the response inhibition impulsivity task and subjective responses to alcohol (i.e. stimulation, sedation and arousal).

resultsThere was a significant positive relationship found between impulsive responding and self-reported sedation following alcohol consumption. Additionally, there was a significant negative relationship between behavioral impulsivity and self-reported stimulation and arousal following alcohol consumption.

conclusionThese results suggest that higher levels of impulsivity are associated with experiencing greater sedating than stimulating effects of alcohol. Individuals with high levels of impulsivity may be less sensitive to the stimulating effects of a specified dose of alcohol, which could lead to these individuals consuming more alcohol to experience the stimulating effects of alcohol.

Indexed as

BehaviorImpulsive BehaviorInhibition, PsychologicalAffectAlcohol DrinkingBreath TestsCentral Nervous System DepressantsEthanolFemaleHumansMalePsychiatric Status Rating ScalesSurveys and QuestionnairesCentral Nervous System DepressantsEthanol

Identifiers

PMID21127353
PMCPMC3002846

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.