Evidence map›Paper›PMID 21126246›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2011

A multiple deficit model of reading disability and attention-deficit/hyperactivity disorder: searching for shared cognitive deficits.

Lauren M McGrath, Bruce F Pennington, Michelle A Shanahan, Laura E Santerre-Lemmon, Holly D Barnard, Erik G Willcutt, John C Defries, Richard K Olson

Abstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The Impact of Intensive Reading Intervention on Level of Attention in Middle School Students.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2015
    Trial
  6. Article
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  8. Review
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  10. Cognitive Profiles of Children with Reading Disabilities and/or ADHD.Behavioral sciences (Basel, Switzerland) · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
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  19. Article
  20. Cerebellar Neuromodulation Impacts Reading Fluency in Young Adults.Neurobiology of language (Cambridge, Mass.) · 2024
    Article

65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Lauren M McGrathMassachusetts General Hospital/Harvard Medical School, USA University of Denver, USA. mcgrath@pngu.mgh.harvard.edu
Bruce F Pennington
Michelle A Shanahan
Laura E Santerre-Lemmon
Holly D Barnard
Erik G Willcutt
John C Defries
Richard K Olson

Funding

VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI ERIK G WILLCUTT · 1990 to 2026
$44.9M
Etiology and Neuropsychology of Math, Reading, ADHD, and their CovariationR01HD068728 · NICHD · UNIVERSITY OF COLORADO · PI PETRILL, STEPHEN A., WILLCUTT, ERIK G · 2011 to 2015
$3.0M
Etiology of Reading Disabilities and Comorbid ADHDR01HD047264 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI WILLCUTT, ERIK G · 2005 to 2009
$2.7M
Validity of DSM-IV ADHD Subtypes in a Community SampleR01MH063941 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI WILLCUTT, ERIK G · 2001 to 2005
$1.7M
DSM-IV ADHD IN AN ETHNICALLY DIVERSE COMMUNITY SAMPLER01MH062120 · NIMH · UNIVERSITY OF COLORADO AT BOULDER · PI WILLCUTT, ERIK G · 2000 to 2004
$1.6M
Genetic Interactions in Developmental DyslexiaF31DC008726 · NIDCD · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI MCGRATH, LAUREN M · 2007 to 2008
$54k
NICHD NIH HHS HD 27802NICHD NIH HHS HD 47264NICHD NIH HHS P50 HD027802NICHD NIH HHS R01 HD047264NICHD NIH HHS R01 HD068728NIDCD NIH HHS DC 87262NIDCD NIH HHS F31 DC008726NIMH NIH HHS MH 62120NIMH NIH HHS MH 63941NIMH NIH HHS R01 MH062120NIMH NIH HHS R01 MH063941
6 · The paper itself

Abstract

backgroundThis study tests a multiple cognitive deficit model of reading disability (RD), attention-deficit/hyperactivity disorder (ADHD), and their comorbidity.

methodsA structural equation model (SEM) of multiple cognitive risk factors and symptom outcome variables was constructed. The model included phonological awareness as a unique predictor of RD and response inhibition as a unique predictor of ADHD. Processing speed, naming speed, and verbal working memory were modeled as potential shared cognitive deficits.

resultsModel fit indices from the SEM indicated satisfactory fit. Closer inspection of the path weights revealed that processing speed was the only cognitive variable with significant unique relationships to RD and ADHD dimensions, particularly inattention. Moreover, the significant correlation between reading and inattention was reduced to non-significance when processing speed was included in the model, suggesting that processing speed primarily accounted for the phenotypic correlation (or comorbidity) between reading and inattention.

conclusionsThis study illustrates the power of a multiple deficit approach to complex developmental disorders and psychopathologies, particularly for exploring comorbidities. The theoretical role of processing speed in the developmental pathways of RD and ADHD and directions for future research are discussed.

Indexed as

CognitionModels, PsychologicalReadingAdolescentAttention Deficit Disorder with HyperactivityChildComorbidityFemaleHumansLearning DisabilitiesMaleMemory, Short-TermNeuropsychological TestsRisk FactorsVerbal Learning

Identifiers

PMID21126246
PMCPMC3079018

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.