ArticleThe Journal of cell biology1990
Identification of actin filaments in the rhabdomeral microvilli of Drosophila photoreceptors.
Article in The Journal of cell biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
35 citing papers in PubMed, 104 citations in OpenAlex.
- Oral Administration of Different Forms of Exogenous Tau Protein Induces Multi-Organ Defects Across Developmental Stages in Drosophila melanogaster.Neurotoxicity research · 2026Article
- N-acetylcysteine suppresses retinal defects in Drosophila models of SNRNP200-associated retinitis pigmentosa.Human molecular genetics · 2026Article
- Spatial arrangement, polarity, and posttranslational modifications of the microtubule system in the Drosophila eye.Cell and tissue research · 2024Article
- Review
- Hydroxylated sphingolipid biosynthesis regulates photoreceptor apical domain morphogenesis.The Journal of cell biology · 2020Article
- One Actor, Multiple Roles: The Performances of Cryptochrome inFrontiers in physiology · 2020Review
- Serial electron microscopic reconstruction of the drosophila larval eye: Photoreceptors with a rudimentary rhabdomere of microvillar-like processes.Developmental biology · 2019Article
- Changes in endolysosomal organization define a pre-degenerative state in the crumbs mutant Drosophila retina.PloS one · 2019Article
- Molecular Chaperone Hsp70 and Its Constitutively Active Form Hsc70 Play an Indispensable Role During Eye Development of Drosophila melanogaster.Molecular neurobiology · 2018Article
- Molecular and functional identification of a novel photopigment inThe Journal of general physiology · 2018Article
- PAR-Complex and Crumbs Function During Photoreceptor Morphogenesis and Retinal Degeneration.Frontiers in cellular neuroscience · 2018Review
- Cryptochrome Interacts With Actin and Enhances Eye-Mediated Light Sensitivity of the Circadian Clock inFrontiers in molecular neuroscience · 2018Article
- A novel function of twins, B subunit of protein phosphatase 2A, in regulating actin polymerization.PloS one · 2017Article
- Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs.Scientific reports · 2016Article
- The actomyosin machinery is required for Drosophila retinal lumen formation.PLoS genetics · 2014Article
- chaoptin, prominin, eyes shut and crumbs form a genetic network controlling the apical compartment of Drosophila photoreceptor cells.Biology open · 2014Article
- Kappe neurons, a novel population of olfactory sensory neurons.Scientific reports · 2014Article
- Drosophila visual transduction.Trends in neurosciences · 2012Review
- PDA (prolonged depolarizing afterpotential)-defective mutants: the story of nina's and ina's--pinta and santa maria, too.Journal of neurogenetics · 2012Review
- Ectoplasm, ghost in the R cell machine?Developmental neurobiology · 2011Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The phototransductive microvilli of arthropod photoreceptors each contain an axial cytoskeleton. The present study shows that actin filaments are a component of this cytoskeleton in Drosophila. Firstly, actin was detected in the rhabdomeral microvilli and in the subrhabdomeral cytoplasm by immunogold labeling with antiactin. Secondly, the rhabdomeres were labeled with phalloidin, indicating the presence of filamentous actin. Finally, the actin filaments were decorated with myosin subfragment-1. The characteristic arrowhead complex formed by subfragment-1 decoration points towards the base of the microvilli, so that the fast growing end of each filament is at the distal end of the microvillus, where it is embedded in a detergent-resistant cap. Each microvillus contains more than one actin filament. Decorated filaments extend the entire length of each microvillus and project into the subrhabdomeral cytoplasm. This organization is comparable to that of the actin filaments in intestinal brush border microvilli. Similar observations were made with the photoreceptor microvilli of the crayfish, Procambarus. Our results provide an indication as to how any myosin that is associated with the rhabdomeres might function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.