Evidence map›Paper›PMID 21124858›Full record

ArticlePloS one2010

Neighborhood socioeconomic deprivation and mortality: NIH-AARP diet and health study.

Jacqueline M Major, Chyke A Doubeni, Neal D Freedman, Yikyung Park, Min Lian, Albert R Hollenbeck, Arthur Schatzkin, Barry I Graubard, Rashmi Sinha

Abstract read
In one paragraph

Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Association of neighborhood economic trajectories and risk of mortality among older adults.Archives of public health = Archives belges de sante publique · 2026
    Article
  8. Article
  9. Assessing Measurement Invariance in Neighborhood Socioeconomic Environment Across Levels of Urbanicity.Journal of urban health : bulletin of the New York Academy of Medicine · 2025
    Article
  10. Social Vulnerability and Disparities in All-Cause Mortality in the United States.Journal of racial and ethnic health disparities · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Assessment of disparities in timely diagnosis and comprehensive workup of cognitive impairment between English and Spanish speakers.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacqueline M MajorDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. Jacqueline.major@nih.gov
Chyke A Doubeni
Neal D Freedman
Yikyung Park
Min Lian
Albert R Hollenbeck
Arthur Schatzkin
Barry I Graubard
Rashmi Sinha

Funding

Prospective Studies of Diet and Cancer in the AARP CohortZIACP010196 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SINHA, RASHMI · 2009 to 2025
$21.0M
Effectiveness of Screening Colonoscopy in Reducing Deaths from Colorectal CancerU01CA151736 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOUBENI, CHYKE ABADAMA · 2011 to 2015
$4.5M
Geographic Disparities in Colorectal Cancer SurvivalR01CA137750 · NCI · WASHINGTON UNIVERSITY · PI SCHOOTMAN, MARIO · 2009 to 2014
$2.0M
Understanding Racial and Ethnic Differences in Survival from Colorectal CancerK01CA127118 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOUBENI, CHYKE ABADAMA · 2007 to 2011
$773k
Intramural NIH HHSNCI NIH HHS K01 CA127118NCI NIH HHS R01 CA137750NCI NIH HHS U01 CA151736
6 · The paper itself

Abstract

purposeResiding in deprived areas may increase risk of mortality beyond that explained by a person's own SES-related factors and lifestyle. The aim of this study was to examine the relation between neighborhood socioeconomic deprivation and all-cause, cancer- and cardiovascular disease (CVD)-specific mortality for men and women after accounting for education and other important person-level risk factors.

methodsIn the longitudinal NIH-AARP Study, we analyzed data from healthy participants, ages 50-71 years at study baseline (1995-1996). Deaths (n = 33831) were identified through December 2005. Information on census tracts was obtained from the 2000 US Census. Cox models estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for quintiles of neighborhood deprivation.

resultsParticipants in the highest quintile of deprivation had elevated risks for overall mortality (HR(men) = 1.17, 95% CI: 1.10, 1.24; HR(women) = 1.13, 95% CI: 1.05, 1.22) and marginally increased risk for cancer deaths (HR(men) = 1.09, 95% CI: 1.00, 1.20; HR(women) = 1.09, 95% CI: 0.99, 1.22). CVD mortality associations appeared stronger in men (HR = 1.33, 95% CI: 1.19, 1.49) than women (HR = 1.18, 95% CI: 1.01, 1.38). There was no evidence of an effect modification by education.

conclusionHigher neighborhood deprivation was associated with modest increases in all-cause, cancer- and CVD-mortality after accounting for many established risk factors.

Indexed as

Residence CharacteristicsAgedCardiovascular DiseasesEducational StatusFemaleHealth StatusHumansLongitudinal StudiesMaleMiddle AgedMortalityMultivariate AnalysisNational Institutes of Health (U.S.)NeoplasmsNutrition AssessmentPrincipal Component Analysis

Identifiers

PMID21124858
PMCPMC2990774

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.