ArticlePloS one2010
Molecular characterization of Borrelia persica, the agent of tick borne relapsing fever in Israel and the Palestinian Authority.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Borrelia theileri infection in beef and dairy cattle in Israel: molecular detection and co-infection with bovine piroplasmids.Parasites & vectors · 2026Article
- Exposure in Horses to Human Tick-Borne Relapsing Fever Agent Borrelia persica, Israel, 2025.Emerging infectious diseases · 2026Article
- Genomic and structural analysis of major antigenic proteins' variability in the human relapsing fever spirocheteCurrent research in microbial sciences · 2026Article
- Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024Review
- Borrelia theileri infections in Rhipicephalus annulatus ticks from the north of Iran.Experimental & applied acarology · 2024Article
- Isolation and Genetic Characterization of the Human Relapsing Fever SpirocheteTransboundary and emerging diseases · 2024Article
- Borrelia persica infection in wild carnivores in Israel: molecular characterization and new potential reservoirs.Parasites & vectors · 2023Article
- Molecular detection and identification of relapsing feverEmerging microbes & infections · 2022Article
- Infection and seroprevalence of Borrelia persica in domestic cats and dogs in Israel.Parasites & vectors · 2022Article
- Review
- Quantitative real-time PCR in Borrelia persica tick-borne relapsing fever demonstrates correlation with the Jarisch-Herxheimer reaction.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Rodent Ectoparasites in the Middle East: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2021Review
- Quality Control in Diagnostic Fluorescence In Situ Hybridization (FISH) in Microbiology.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Screening for infectious diseases among newly arrived asylum seekers, Bavaria, Germany, 2015.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2018Article
- Case Report: Infectious Diseases in Pilgrims Visiting the Holy Land.The American journal of tropical medicine and hygiene · 2017Article
- Borrelia persica infection in dogs and cats: clinical manifestations, clinicopathological findings and genetic characterization.Parasites & vectors · 2016Article
- African swine fever.EFSA journal. European Food Safety Authority · 2015Article
- Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation.BMC genomics · 2013Article
- Relapsing fever borreliae in Africa.The American journal of tropical medicine and hygiene · 2013Review
- Phylogenetic analysis of the spirochete Borrelia microti, a potential agent of relapsing fever in Iran.Journal of clinical microbiology · 2012Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identification of the Tick Borne Relapsing Fever (TBRF) agent in Israel and the Palestinian Authority relies on the morphology and the association of Borrelia persica with its vector Ornithodoros tholozani. Molecular based data on B. persica are very scarce as the organism is still non-cultivable. In this study, we were able to sequence three complete 16S rRNA genes, 12 partial flaB genes, 18 partial glpQ genes, 16 rrs-ileT intergenic spacers (IGS) from nine ticks and ten human blood samples originating from the West Bank and Israel. In one sample we sequenced 7231 contiguous base pairs that covered completely the region from the 5'end of the 16S rRNA gene to the 5'end of the 23S rRNA gene comprising the whole 16S rRNA (rrs), and the following genes: Ala tRNA (alaT), Ile tRNA (ileT), adenylosuccinate lyase (purB), adenylosuccinate synthetase (purA), methylpurine-DNA glycosylase (mag), hypoxanthine-guanine phosphoribosyltransferase (hpt), an hydrolase (HAD superfamily) and a 135 bp 5' fragment of the 23S rRNA (rrlA) genes. Phylogenic sequence analysis defined all the Borrelia isolates from O. tholozani and from human TBRF cases in Israel and the West Bank as B. persica that clustered between the African and the New World TBRF species. Gene organization of the intergenic spacer between the 16S rRNA and the 23S rRNA was similar to that of other TBRF Borrelia species and different from the Lyme disease Borrelia species. Variants of B. persica were found among the different genes of the different isolates even in the same sampling area.
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