ArticleClinical medicine insights. Arthritis and musculoskeletal disorders2010
Pattern of Young and Old Onset Rheumatoid Arthritis (YORA and EORA) Among a Group of Egyptian Patients with Rheumatoid Arthritis.
Article in Clinical medicine insights. Arthritis and musculoskeletal disorders, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Late-onset versus young-onset rheumatoid arthritis in South Africans.Clinical rheumatology · 2026Article
- Clinical and Sonographic Pattern of Late-Onset and Early-Onset Rheumatoid Arthritis: Comparative Study.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026Article
- Study of rheumatoid arthritis in older patients: a cross-sectional study.BMC geriatrics · 2025Article
- Pathophysiology of Myopenia in rheumatoid arthritis.Bone research · 2025Review
- Incidence Trends of Rheumatoid Arthritis in Korea for 11 Years (2006-2017).Clinics and practice · 2024Article
- Review
- Response: Eccentric Versus Concentric Exercises in Patients With Rheumatoid Arthritis and Rotator Cuff Tendinopathy: A Randomized Comparative Study (Ann Rehabil Med 2023;47:26-35).Annals of rehabilitation medicine · 2024Article
- Sarcopenia and Nutrition in Elderly Rheumatoid Arthritis Patients: A Cross-Sectional Study to Determine Prevalence and Risk Factors.Nutrients · 2023Article
- Eccentric Versus Concentric Exercises in Patients With Rheumatoid Arthritis and Rotator Cuff Tendinopathy: A Randomized Comparative Study.Annals of rehabilitation medicine · 2023Article
- Static Foot Disturbances and the Quality of Life of Older Person with Rheumatoid Arthritis.International journal of environmental research and public health · 2022Article
- Patients with early-onset primary Sjögren's syndrome have distinctive clinical manifestations and circulating lymphocyte profiles.Rheumatology (Oxford, England) · 2022Article
- Inflammatory profile of incident cases of late-onset compared with young-onset rheumatoid arthritis: A nested cohort study.Frontiers in medicine · 2022Article
- Rheumatoid Arthritis Onset from Shoulder Monoarthritis.Open access rheumatology : research and reviews · 2021Article
- Acetabular cup migration after primary cementless total hip arthroplasty in rheumatoid arthritis and its influencing factors: a comparative study with osteoarthritic hip.International orthopaedics · 2020Article
- Management of inflammatory rheumatic conditions in the elderly.Rheumatology (Oxford, England) · 2019Review
- The influence of age at disease onset on disease activity and disability: results from the Ontario Best Practices Research Initiative.Clinical rheumatology · 2016Article
- Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis.Arthritis research & therapy · 2015Article
- Optimizing perioperative outcomes for older patients with rheumatoid arthritis undergoing arthroplasty: emphasis on medication management.Drugs & aging · 2015Review
- Bone mineral density loss in postmenopausal onset rheumatoid arthritis is not greater than premenopausal onset disease.Caspian journal of internal medicine · 2014Article
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5 authors.
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Abstract
objectiveRheumatoid arthritis (RA) differs depending on the age of disease onset. The differences between EORA and YORA are important because they have clinical and therapeutic implications.
method1185 patients were ranked after classification according to age at onset of the disease into YORA I (16-40 years), YORA II (41-60 years) and EORA >60 years. All patients groups were compared, based on disease duration, disease activity, severity parameters and drug history.
resultsYORA I included 298 patients, 28.85% were males, with mean age of 29.4 ± 6 years and disease duration 4 ± 3.3 y, YORA II included 539 patients, 33.77% males, age 49.7 ± 6.1 y and disease duration 6.5 ± 5.6 y. EORA included 348 RA patients 40.5% males, age 67.1 ± 6.6 y, disease duration 9.95 ± 7.2 y. Activity was increased in EORA compared to YORA I and YORA II, while severity decreased in EORA. ESR, CRP and degree of anemia were higher in EORA. RF titer was higher in YORA. Small joints of the hands and feet were more involved in YORA, while, large joints in EORA. Rheumatoid nodules were increased in YORA I than EORA P = 0.04. Polymyalgia rheumatica was exclusively present in EORA group 25 patients 7.2%. Methotrexate was used in both YORA and EORA, with a higher mean of dosage in YORA than EORA. Multiple DMARDs in EORA was 57.9%, and biologics in 0.8% was which was significantly lower compared with YORA I, 86.3% and 1.7%, with P = 0.001.
conclusionEORA has more active and less disabling and affects more males than YORA. The use of biologic therapy and combination DMARD therapy was less in EORA.
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