Evidence map›Paper›PMID 21124260›Full record

Trial reportSpine2011

Predominant leg pain is associated with better surgical outcomes in degenerative spondylolisthesis and spinal stenosis: results from the Spine Patient Outcomes Research Trial (SPORT).

Adam Pearson, Emily Blood, Jon Lurie, William Abdu, Dilip Sengupta, John W Frymoyer, James Weinstein

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Spine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 3 syntheses or guidelines pooled it, 107 citations in OpenAlex.

  1. Surgery for adult spondylolisthesis: a systematic review of the evidence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2016
    Pooled it
  2. Surgical versus non-surgical treatment for lumbar spinal stenosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  3. Management of lumbar spinal stenosis.BMJ (Clinical research ed.) · 2016
    Pooled it
  4. Trial
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  8. Degenerative lumbar spondylolisthesis: review of current classifications and proposal of a novel classification system.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Review
  9. Preoperative fatty infiltration of paraspinal muscles assessed by MRI is associated with less improvement of leg pain 2 years after surgery for lumbar spinal stenosis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Adam PearsonDepartment of Medicine, Dartmouth-HitchcockMedical Center, Lebanon, NH 03756, USA. adam.m.pearson@hitchcock.org
Emily Blood
Jon Lurie
William Abdu
Dilip Sengupta
John W Frymoyer
James Weinstein
Dartmouth–Hitchcock Medical Center · USDartmouth Institute for Health Policy and Clinical Practice · US

Funding

LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIALU01AR045444 · NIAMS · DARTMOUTH COLLEGE · PI WEINSTEIN, JAMES N · 1999 to 2013
$20.8M
Prognostic Value of Lumbar Spine MRIP60AR048094 · NIAMS · DARTMOUTH COLLEGE · PI ATLAS, STEVEN J · 2003 to 2007
$6.2M
The Dartmouth Orthopaedics Clinician/Researcher Training Program (DOC/RTP)T32AR049710 · NIAMS · DARTMOUTH-HITCHCOCK CLINIC · PI LURIE, JON D · 2003 to 2018
$2.4M
NIAMS NIH HHS P60 AR048094NIAMS NIH HHS T32 AR049710NIAMS NIH HHS U01 AR045444NIAMS NIH HHS U01-AR45444
6 · The paper itself

Abstract

STUDY

designAs-treated analysis of the Spine Patient Outcomes Research Trial.

objectiveTo compare baseline characteristics and surgical and nonoperative outcomes in degenerative spondylolisthesis (DS) and spinal stenosis (SpS) patients stratified by predominant pain location (i.e., leg vs. back). SUMMARY OF BACKGROUND DATA: Evidence suggests that DS and SpS patients with predominant leg pain may have better surgical outcomes than patients with predominant low back pain (LBP).

methodsThe DS cohort included 591 patients (62% underwent surgery), and the SpS cohort included 615 patients (62% underwent surgery). Patients were classified as leg pain predominant, LBP predominant, or having equal pain according to baseline pain scores. Baseline characteristics were compared between the 3 predominant pain location groups within each diagnostic category, and changes in surgical and nonoperative outcome scores were compared for 2 years. Longitudinal regression models including baseline covariates were used to control for confounders.

resultsAmong DS patients at baseline, 34% had predominant leg pain, 26% had predominant LBP, and 40% had equal pain. Similarly, 32% of SpS patients had predominant leg pain, 26% had predominant LBP, and 42% had equal pain. DS and SpS patients with predominant leg pain had baseline scores indicative of less severe symptoms. Leg pain predominant DS and SpS patients treated surgically improved significantly more than LBP predominant patients on all primary outcome measures at 1 and 2 years. Surgical outcomes for the equal pain groups were intermediate to those of the predominant leg pain and LBP groups. The differences in nonoperative outcomes were less consistent. Conclusion. Predominant leg pain patients improved significantly more with surgery than predominant LBP patients. However, predominant LBP patients still improved significantly more with surgery than with nonoperative treatment.

Indexed as

LegPain MeasurementAgedCohort StudiesCross-Over StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedPainSpinal StenosisSpineSpondylolisthesisTreatment Outcome

Identifiers

PMID21124260
PMCPMC3057763
OpenAlexW1964114450

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.