ArticleEmerging infectious diseases2010
Pandemic (H1N1) 2009 infection in patients with hematologic malignancy.
Article in Emerging infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 18 citations in OpenAlex.
- A prospective study of the factors shaping antibody responses to the AS03-adjuvanted influenza A/H1N1 vaccine in cancer outpatients.The oncologist · 2012Trial
- Influenza in patients with cancer after 2009 pandemic AH1N1: An 8-year follow-up study in Mexico.Influenza and other respiratory viruses · 2020Article
- Influenza in patients with hematological malignancies: Experience at two comprehensive cancer centers.Journal of medical virology · 2018Article
- Immunogenicity of a monovalent influenza A(H1N1)pdm09 vaccine in patients with hematological malignancies.Human vaccines & immunotherapeutics · 2014Article
- Unchanged severity of influenza A(H1N1)pdm09 infection in children during first postpandemic season.Emerging infectious diseases · 2012Article
- Changing epidemiology of respiratory viral infections in hematopoietic cell transplant recipients and solid organ transplant recipients.Current opinion in infectious diseases · 2011Review
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To assess outcomes of patients with hematologic malignancy and pandemic (H1N1) 2009 infection, we reviewed cases during June-December 2009 at the University of California San Francisco Medical Center. Seventeen (63%) and 10 (37%) patients had upper respiratory tract infection (URTI) and lower respiratory tract infection (LRTI), respectively. Cough (85%) and fever (70%) were the most common signs; 19% of patients had nausea, vomiting, or diarrhea. Sixty-five percent of URTI patients were outpatients; 35% recovered without antiviral therapy. All LRTI patients were hospitalized; half required intensive care unit admission. Complications included acute respiratory distress syndrome, pneumomediastinum, myocarditis, and development of oseltamivir-resistant virus; 3 patients died. Of the 3 patients with nosocomial pandemic (H1N1) 2009, 2 died. Pandemic (H1N1) 2009 may cause serious illness in patients with hematologic malignancy, primarily those with LRTI. Rigorous infection control, improved techniques for diagnosing respiratory disease, and early antiviral therapy can prevent nosocomial transmission and optimize patient care.
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