ArticleBMC plant biology2010
Proteomic characterization of iron deficiency responses in Cucumis sativus L. roots.
Article in BMC plant biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 85 citations in OpenAlex.
- Molecular Mechanism by Which the BrFIT2-BrbHLH-BrIRT1 Module Synergistically Regulates Iron Absorption in Brassica rapa ssp. Pekinensis.Plant biotechnology journal · 2025Article
- Micronutrient deficiency-induced oxidative stress in plants.Plant cell reports · 2024Review
- A systematicFrontiers in plant science · 2023Article
- Effect of the Interaction between Elevated Carbon Dioxide and Iron Limitation on Proteomic Profiling of Soybean.International journal of molecular sciences · 2022Article
- Proteomic and Genomic Studies of Micronutrient Deficiency and Toxicity in Plants.Plants (Basel, Switzerland) · 2022Review
- Serial-Omics and Molecular Function Study Provide Novel Insight into Cucumber Variety Improvement.Plants (Basel, Switzerland) · 2022Review
- Genomically Hardwired Regulation of Gene Activity Orchestrates Cellular Iron Homeostasis in Arabidopsis.RNA biology · 2022Article
- Regional Heritability Mapping of Quantitative Trait Loci Controlling Traits Related to Growth and Productivity in Popcorn (Plants (Basel, Switzerland) · 2021Article
- Iron Deficiency Leads to Chlorosis Through Impacting Chlorophyll Synthesis and Nitrogen Metabolism inFrontiers in plant science · 2021Article
- Iron deficiency triggered transcriptome changes in bread wheat.Computational and structural biotechnology journal · 2020Article
- Common and specific responses to iron and phosphorus deficiencies in roots of apple tree (Malus × domestica).Plant molecular biology · 2019Article
- The Understanding of the Plant Iron Deficiency Responses in Strategy I Plants and the Role of Ethylene in This Process by Omic Approaches.Frontiers in plant science · 2017Review
- Root proteomics reveals cucumber 24-epibrassinolide responses under Ca(NO3)2 stress.Plant cell reports · 2016Article
- Transcriptional Characterization of a Widely-Used Grapevine Rootstock Genotype under Different Iron-Limited Conditions.Frontiers in plant science · 2016Article
- Changes in the transcriptomic profiles of maize roots in response to iron-deficiency stress.Plant molecular biology · 2014Article
- SORTING NEXIN1 is required for modulating the trafficking and stability of the Arabidopsis IRON-REGULATED TRANSPORTER1.The Plant cell · 2014Article
- Searching iron sensors in plants by exploring the link among 2'-OG-dependent dioxygenases, the iron deficiency response and metabolic adjustments occurring under iron deficiency.Frontiers in plant science · 2013Article
- Iron deficiency in plants: an insight from proteomic approaches.Frontiers in plant science · 2013Article
- A small-scale proteomic approach reveals a survival strategy, including a reduction in alkaloid biosynthesis, in Hyoscyamus albus roots subjected to iron deficiency.Frontiers in plant science · 2013Article
- Iron deficiency affects nitrogen metabolism in cucumber (Cucumis sativus L.) plants.BMC plant biology · 2012Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIron deficiency induces in Strategy I plants physiological, biochemical and molecular modifications capable to increase iron uptake from the rhizosphere. This effort needs a reorganization of metabolic pathways to efficiently sustain activities linked to the acquisition of iron; in fact, carbohydrates and the energetic metabolism has been shown to be involved in these responses. The aim of this work was to find both a confirmation of the already expected change in the enzyme concentrations induced in cucumber root tissue in response to iron deficiency as well as to find new insights on the involvement of other pathways.
resultsThe proteome pattern of soluble cytosolic proteins extracted from roots was obtained by 2-DE. Of about two thousand spots found, only those showing at least a two-fold increase or decrease in the concentration were considered for subsequent identification by mass spectrometry. Fifty-seven proteins showed significant changes, and 44 of them were identified. Twenty-one of them were increased in quantity, whereas 23 were decreased in quantity. Most of the increased proteins belong to glycolysis and nitrogen metabolism in agreement with the biochemical evidence. On the other hand, the proteins being decreased belong to the metabolism of sucrose and complex structural carbohydrates and to structural proteins.
conclusionsThe new available techniques allow to cast new light on the mechanisms involved in the changes occurring in plants under iron deficiency. The data obtained from this proteomic study confirm the metabolic changes occurring in cucumber as a response to Fe deficiency. Two main conclusions may be drawn. The first one is the confirmation of the increase in the glycolytic flux and in the anaerobic metabolism to sustain the energetic effort the Fe-deficient plants must undertake. The second conclusion is, on one hand, the decrease in the amount of enzymes linked to the biosynthesis of complex carbohydrates of the cell wall, and, on the other hand, the increase in enzymes linked to the turnover of proteins.
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