Evidence map›Paper›PMID 21121836›Full record

ReviewThe New England journal of medicine2010

Airway mucus function and dysfunction.

John V Fahy, Burton F Dickey

2 registry-linked trialsAbstract readReview
In one paragraph

Review in The New England journal of medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 896 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
896citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05480371 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Role of Cough Assist Device in Mechanically Ventilated Patients in Respiratory Intensive Care Unit : Assiut University Experience

TypeinterventionalSponsorAssiut UniversityRan2022 to 2023Enrolled200ConditionsMechanically Ventilated PatientsArmsConventional tracheal suctioning, Mechanical insufflation/exsufflation
NCT05546645 unknown statusnot on this mapstarted 2023, after this paper: background citation

Validation of a Questionnaire to Assess Bronchial Mucus Hypersecretion in Asthmatic Patients. Questionnaire "T-sec" (Secretion Test).

TypeobservationalSponsorFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauRan2023 to 2024Enrolled100ConditionsAsthmaArmsQuestionnaire
3 · Its place in the literature

Who cites it

896 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Potassium Channels of the Airway Epithelium.Acta physiologica (Oxford, England) · 2026
    Review
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836 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

John V FahyCardiovascular Research Institute and Department of Medicine, University of California, San Francisco, USA.
Burton F Dickey

Funding

Role of miRNAs in Th2-Driven inflammation in AsthmaP01HL107202 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANSEL, KARL MARK · 2012 to 2023
$23.3M
Preventing fucose-dependent binding of aspergillus and pseudomonas to lung mucinP50HL107191 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FAHY, JOHN V · 2011 to 2012
$848k
NHLBI NIH HHS P01 HL107202NHLBI NIH HHS P50 HL107191
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaCystic FibrosisHumansLung DiseasesMucociliary ClearanceMucusPulmonary Disease, Chronic ObstructiveRespiratory Physiological PhenomenaRespiratory System

Identifiers

PMID21121836
PMCPMC4048736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.