Evidence map›Paper›PMID 21121277›Full record

ReviewJournal of nanoscience and nanotechnology2010

Cell-penetrating peptide-functionalized quantum dots for intracellular delivery.

Betty R Liu, Yue-Wern Huang, Huey-Jenn Chiang, Han-Jung Lee

Abstract readReview
In one paragraph

Review in Journal of nanoscience and nanotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Inhibition of regulated cell death by cell-penetrating peptides.Cellular and molecular life sciences : CMLS · 2016
    Review
  4. Article
  5. Review
  6. Article
  7. Peptide-lipid interactions: experiments and applications.International journal of molecular sciences · 2013
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Betty R LiuDepartment of Natural Resources and Environmental Studies, National Dong Hwa University, Hualien 97401, Taiwan.
Yue-Wern Huang
Huey-Jenn Chiang
Han-Jung Lee

Funding

Quantum Dots and Protein Transduction Domains as a Biomolecule Delivery VehicleR15EB009530 · NIBIB · MISSOURI UNIVERSITY OF SCIENCE & TECHNOLOGY · PI HUANG, YUE-WERN · 2009 to 2009
$226k
NIBIB NIH HHS R15 EB009530NIBIB NIH HHS R15EB009530
6 · The paper itself

Abstract

Quantum dots (QDs) are luminescent semiconductor nanocrystals that are widely used as fluorescent probes in biomedical applications, including cellular imaging and tumor tracking. Cell-penetrating peptides (CPPs), also called protein transduction domains (PTDs), are short basic peptides that permeate cell membranes and are able to deliver a variety of macromolecule cargoes, such as DNAs, RNAs, proteins, and nanomaterials. Here we review strategies to couple QDs to CPPs, by either covalent linkages or noncovalent interactions, to provide a tool to study intracellular delivery. This facilitated transport of QDs by CPPs into cells is both simple and efficient. Accordingly, CPP-QD nanoparticles are likely to be of broad utility in biological research and advance the development of medical and pharmaceutical therapeutics.

Indexed as

Quantum DotsCell-Penetrating PeptidesDrug Delivery SystemsNanocompositesPinocytosisProtein TransportCell-Penetrating Peptides

Identifiers

PMID21121277
PMCPMC2999507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.