Evidence map›Paper›PMID 21119020›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2010

The accessory genome of Pseudomonas aeruginosa.

Vanderlene L Kung, Egon A Ozer, Alan R Hauser

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 182 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
182citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

182 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. The impact of modulator therapy on theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Horizontal transfer of ICEJournal of bacteriology · 2026
    Article
  6. Beyond the Usual Suspects: EmergingInternational journal of molecular sciences · 2026
    Review
  7. Antibiotic resistance mechanisms and global resistance patterns of Pseudomonas aeruginosa in microbial keratitis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Comparative Genomic Analysis ofInfection and drug resistance · 2026
    Article
  12. Within-host adaptation mutations associated with persistent colonization ofFrontiers in cellular and infection microbiology · 2026
    Article
  13. Article
  14. Predicting Strain-Specific Metabolic Capabilities in the GenusComputational and structural biotechnology journal · 2026
    Article
  15. Structural and functional insights into Pseudomonas aeruginosa's secretion systems 1-6: regulation, role in microbial keratitis and drug targets.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  16. Adaptive evolution ofMicrobial genomics · 2026
    Article
  17. Article
  18. Genomic islands inNAR genomics and bioinformatics · 2025
    Article
  19. Article
  20. Article

122 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vanderlene L KungDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. ahauser@northwestern.edu.
Egon A Ozer
Alan R Hauser

Funding

TRAINING PROGRAM IN IMMUNOLOGY &MOLECULAR PATHOGENESIST32AI007476 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Edward Benjamin Thorp · 1996 to 2026
$6.6M
Mechanistic Studies of Patatin-like ToxinsR01AI053674 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2003 to 2017
$4.3M
Pseudomonas aeruginosa Genomic Islands and VirulenceR01AI075191 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2009 to 2013
$1.7M
Novel Pathogenicity islands of Pseudomonas aeruginosaK02AI065615 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2005 to 2009
$496k
Mechanism of Azithromycin Activity in Pseudomonas InfectionsR21AI088286 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HAUSER, ALAN R · 2010 to 2011
$438k
Pseudomonas aeruginosa genomic islands and virulence factorsF30ES016487 · NIEHS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KUNG, VANDERLENE LIU · 2008 to 2011
$162k
Identifying novel Pseudomonas Aeruginosa pathogenesis-associated genomic islandsF32AI089068 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI OZER, EGON ANDERSON · 2010 to 2011
$107k
NIAID NIH HHS 1R01 AI075191NIAID NIH HHS 1R21 AI088286NIAID NIH HHS 2R01 AI053674NIAID NIH HHS 5K02 AI065615NIAID NIH HHS 5T32 AI007476-13NIAID NIH HHS F32 AI089068NIAID NIH HHS K02 AI065615NIAID NIH HHS R01 AI053674NIAID NIH HHS R01 AI075191NIAID NIH HHS R21 AI088286NIAID NIH HHS T32 AI007476NIEHS NIH HHS 5F30 ES016487-03NIEHS NIH HHS F30 ES016487
6 · The paper itself

Abstract

Pseudomonas aeruginosa strains exhibit significant variability in pathogenicity and ecological flexibility. Such interstrain differences reflect the dynamic nature of the P. aeruginosa genome, which is composed of a relatively invariable "core genome" and a highly variable "accessory genome." Here we review the major classes of genetic elements comprising the P. aeruginosa accessory genome and highlight emerging themes in the acquisition and functional importance of these elements. Although the precise phenotypes endowed by the majority of the P. aeruginosa accessory genome have yet to be determined, rapid progress is being made, and a clearer understanding of the role of the P. aeruginosa accessory genome in ecology and infection is emerging.

Indexed as

Genome, BacterialDNA Transposable ElementsEvolution, MolecularGene Transfer, HorizontalGenomic IslandsProphagesPseudomonas aeruginosaPseudomonas InfectionsDNA Transposable Elements

Identifiers

PMID21119020
PMCPMC3008168

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.