ArticleHeart rhythm2011
Patterns of baseline autonomic nerve activity and the development of pacing-induced sustained atrial fibrillation.
Article in Heart rhythm, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 62 citations in OpenAlex.
- Single-cell RNA sequencing identifies a peripheral monocyte subpopulation and its interaction with atrial macrophages via the CCL3-CCR1 axis during atrial remodeling.Science China. Life sciences · 2025Article
- Ganglionated plexus ablation and pulmonary vein isolation: the future of AF ablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- The application and mechanism of Chinese medicine in the upstream treatment of atrial fibrillation.Frontiers in cardiovascular medicine · 2023Review
- Colchicine in Cardiac Surgery: The COCS Randomized Clinical Trial.Journal of cardiovascular development and disease · 2022Article
- Immune remodeling and atrial fibrillation.Frontiers in physiology · 2022Review
- Immunothrombosis and new-onset atrial fibrillation in the general population: the Rotterdam Study.Clinical research in cardiology : official journal of the German Cardiac Society · 2022Article
- The cardiac autonomic nervous system: an introduction.Herzschrittmachertherapie & Elektrophysiologie · 2021Review
- Association of furosemide or hydrochlorothiazide use with risk of atrial fibrillation post pacemaker implantation among elderly patients.Annals of translational medicine · 2021Article
- Irritant Inhalation Evokes P Wave Morphological Changes in Spontaneously Hypertensive Rats via Reflex Modulation of the Autonomic Nervous System.Frontiers in physiology · 2021Article
- The cardiac autonomic nervous system: A target for modulation of atrial fibrillation.Clinical cardiology · 2019Review
- Understanding the Beat-to-Beat Variations of P-Waves Morphologies in AF Patients During Sinus Rhythm: A Scoping Review of the Atrial Simulation Studies.Frontiers in physiology · 2019Article
- Atrial fibrillation and chronic kidney disease: A bad combination.Kidney research and clinical practice · 2018Article
- Ganglionated plexi as neuromodulation targets for atrial fibrillation.Journal of cardiovascular electrophysiology · 2017Review
- Atrial fibrillation: mechanisms, therapeutics, and future directions.Comprehensive Physiology · 2015Review
- Estimating sympathetic tone by recording subcutaneous nerve activity in ambulatory dogs.Journal of cardiovascular electrophysiology · 2015Article
- Renal Denervation And Pulmonary Vein Isolation In Patients With Drug Resistant Hypertension And Symptomatic Atrial Fibrillation.Journal of atrial fibrillation · 2014Review
- Effects of carvedilol on cardiac autonomic nerve activities during sinus rhythm and atrial fibrillation in ambulatory dogs.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2014Article
- Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy.Circulation research · 2014Review
- Autonomic nerve activity and blood pressure in ambulatory dogs.Heart rhythm · 2014Article
- The Propensity for Inducing Atrial Fibrillation: A Comparative Study on Old versus Young Rabbits.Journal of aging research · 2014Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWhether autonomic nerve activity is important in the development of pacing-induced sustained atrial fibrillation (AF) is unclear.
objectiveThe purpose of this study was to test the hypothesis that patterns of baseline autonomic nerve activity are important in the development of pacing-induced sustained AF.
methodsRadiotransmitters were implanted in 12 ambulatory dogs to record left stellate ganglion nerve activity (SGNA) and vagal nerve activity (VNA). Sustained (>48 hours) AF was induced with intermittent rapid atrial pacing.
resultsAt baseline (before pacing), 1-minute integrated nerve activity between SGNA and VNA demonstrated either a single linear relationship with excellent correlation (group 1, N = 3, r = 0.816 ± 0.105) or nonlinear relationships with poor correlation (group 2, N = 9, r = 0.316 ± 0.162, P <.05 vs group 1). Group 1 dogs had higher VNA (97.0 ± 11.5 mV-s) compared to group 2 (33.4 ± 21.7 mV-s, P <.001). Group 1 dogs had more frequent sympathovagal co-activation episodes than did group 2 (50 ± 19 per day vs 15 ± 6 per day, P <.05) and more paroxysmal atrial tachycardia (PAT; 5 ± 1 per day vs 2 ± 1 per day, P <.05) at baseline. Sustained AF occurred after 16 ± 4 days (range 13-20 days) of pacing in group 1 and after 46 ± 18 days (range 23-72 days) of pacing in group 2 (P <.05). In the week before development of sustained AF, VNA of group 2 dogs was significantly increased compared to baseline (P <.05).
conclusionAmbulatory dogs with good linear sympathovagal correlation and higher vagal tone at baseline have more PAT episodes at baseline and faster induction of sustained AF by rapid pacing. Rapid atrial pacing increased the VNA of the remaining dogs before induction of sustained AF.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.