ArticleParasitology2011
Genome sequences reveal divergence times of malaria parasite lineages.
Article in Parasitology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 49 citations in OpenAlex.
- Article
- Phylogenetic congruence of Plasmodium spp. and wild ungulate hosts in the Peruvian Amazon.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2024Article
- The Piroplasmida Babesia, Cytauxzoon, and Theileria in farm and companion animals: species compilation, molecular phylogeny, and evolutionary insights.Parasitology research · 2022Review
- Host-parasite co-evolution and its genomic signature.Nature reviews. Genetics · 2020Review
- Article
- Immunogenicity analysis of genetically conserved segments in Plasmodium ovale merozoite surface protein-8.Parasites & vectors · 2019Article
- Transcriptome and Proteome Response ofFrontiers in physiology · 2019Article
- Limited genetic diversity of N-terminal of merozoite surface protein-1 (MSP-1) in Plasmodium ovale curtisi and P. ovale wallikeri imported from Africa to China.Parasites & vectors · 2018Article
- Wild bonobos host geographically restricted malaria parasites including a putative new Laverania species.Nature communications · 2017Article
- The Genome of Haemoproteus tartakovskyi and Its Relationship to Human Malaria Parasites.Genome biology and evolution · 2016Article
- Endogenously-expressed NH2-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands.Malaria journal · 2016Article
- De novo assembly and transcriptome analysis of Plasmodium gallinaceum identifies the Rh5 interacting protein (ripr), and reveals a lack of EBL and RH gene family diversification.Malaria journal · 2015Article
- A new method for estimating species age supports the coexistence of malaria parasites and their Mammalian hosts.Molecular biology and evolution · 2015Article
- Review
- Diversification of the Genus Anopheles and a Neotropical Clade from the Late Cretaceous.PloS one · 2015Article
- Finding connections in the unexpected detection of Plasmodium vivax and Plasmodium falciparum DNA in asymptomatic blood donors: a fact in the Atlantic Forest.Malaria journal · 2014Article
- The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems.Nucleic acids research · 2014Article
- Malarial hemozoin: from target to tool.Biochimica et biophysica acta · 2014Review
- Deep profiling of the novel intermediate-size noncoding RNAs in intraerythrocytic Plasmodium falciparum.PloS one · 2014Article
- A novel clade of unique eukaryotic ribonucleotide reductase R2 subunits is exclusive to apicomplexan parasites.Journal of molecular evolution · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveThe evolutionary history of human malaria parasites (genus Plasmodium) has long been a subject of speculation and controversy. The complete genome sequences of the two most widespread human malaria parasites, P. falciparum and P. vivax, and of the monkey parasite P. knowlesi are now available, together with the draft genomes of the chimpanzee parasite P. reichenowi, three rodent parasites, P. yoelii yoelli, P. berghei and P. chabaudi chabaudi, and one avian parasite, P. gallinaceum.
methodsWe present here an analysis of 45 orthologous gene sequences across the eight species that resolves the relationships of major Plasmodium lineages, and provides the first comprehensive dating of the age of those groups.
resultsOur analyses support the hypothesis that the last common ancestor of P. falciparum and the chimpanzee parasite P. reichenowi occurred around the time of the human-chimpanzee divergence. P. falciparum infections of African apes are most likely derived from humans and not the other way around. On the other hand, P. vivax, split from the monkey parasite P. knowlesi in the much more distant past, during the time that encompasses the separation of the Great Apes and Old World Monkeys.
conclusionThe results support an ancient association between malaria parasites and their primate hosts, including humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.