Evidence map›Paper›PMID 21118273›Full record

ReviewAlcoholism, clinical and experimental research2011

Alcohol exposure and mechanisms of tissue injury and repair.

M Katherine Jung, John J Callaci, Kristen L Lauing, Jeffrey S Otis, Katherine A Radek, Michael K Jones, Elizabeth J Kovacs

Open access · greenAbstract readReview
In one paragraph

Review in Alcoholism, clinical and experimental research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
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  15. Article
  16. Review
  17. Article
  18. Article
  19. Advances in Relationship Between Alcohol Consumption and Skin Diseases.Clinical, cosmetic and investigational dermatology · 2023
    Review
  20. Investigation of the hemostatic mechanism ofAnnals of translational medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

M Katherine JungDivision of Metabolism and Health Effects, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892-9304, USA. jungma@mail.nih.gov
John J Callaci
Kristen L Lauing
Jeffrey S Otis
Katherine A Radek
Michael K Jones
Elizabeth J Kovacs
Loyola University Chicago · USNational Institute on Alcohol Abuse and Alcoholism · USEmory University · USUniversity of California, San Diego · USVA San Diego Healthcare System · US

Funding

Training in Neuroimmunoendocrine Effects of AlcoholT32AA013527 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI CHOUDHRY, MASHKOOR A · 2002 to 2021
$4.4M
ETHANOL EFFECTS ON RECOVERY FROM THERMAL INJURYR01AA012034 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI KOVACS, ELIZABETH J. · 1999 to 2012
$4.2M
Alcohol Injury Healing, Cytoprotection and SurvivinR01AA014946 · NIAAA · SOUTHERN CALIFORNIA INST FOR RES/EDUC · PI JONES, MICHAEL K · 2005 to 2009
$1.1M
Classifying Binge Alcohol-Induced Bone DamageR01AA016138 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI CALLACI, JOHN J. · 2006 to 2009
$987k
Loyola Alcohol Research Center (LARC)P30AA019373 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI KOVACS, ELIZABETH J. · 2009 to 2010
$832k
Chronic alcohol-induced skeletal muscle myopathy: etiology & physiologyK01AA017190 · NIAAA · GEORGIA STATE UNIVERSITY · PI OTIS, JEFFREY S · 2008 to 2012
$579k
The effects of acute binge alcohol exposure on the canonical Wnt signaling pathwaF31AA019613 · NIAAA · LOYOLA UNIVERSITY CHICAGO · PI LAUING, KRISTEN LEIGH · 2010 to 2011
$56k
NIAAA NIH HHS F31 AA019613NIAAA NIH HHS K01 AA017190NIAAA NIH HHS K01AA017190NIAAA NIH HHS P30 AA019373NIAAA NIH HHS P30AA019373NIAAA NIH HHS R01 AA012034NIAAA NIH HHS R01AA012034NIAAA NIH HHS R01 AA014946NIAAA NIH HHS R01AA014946NIAAA NIH HHS R01 AA016138NIAAA NIH HHS R01AA016138NIAAA NIH HHS T32 AA013527NIAAA NIH HHS T32AA013527
6 · The paper itself

Abstract

Tissue injury owing to acute and chronic alcohol consumption has extensive medical consequences, with the level and duration of alcohol exposure affecting both the magnitude of injury and the time frame to recovery. While the understanding of many of the molecular processes disrupted by alcohol has advanced, mechanisms of alcohol-induced tissue injury remain a subject of intensive research. Alcohol has multiple targets, as it affects diverse cellular and molecular processes. Some mechanisms of tissue damage as a result of alcohol may be common to many tissue types, while others are likely to be tissue specific. Here, we present a discussion of the alcohol-induced molecular and cellular disruptions associated with injury or recovery from injury in bone, muscle, skin, and gastric mucosa. In every case, the goal of characterizing the sites of alcohol action is to devise potential measures for protection, prevention, or therapeutic intervention.

Indexed as

Alcohol DrinkingAlcoholismAnimalsEthanolHumansWound HealingEthanol

Identifiers

PMID21118273
PMCPMC3117956
OpenAlexW1882858707

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.