Evidence map›Paper›PMID 21118148›Full record

ReviewBiochemical Society transactions2010

Mechanisms of metal-induced centrosome amplification.

Amie L Holmes, John Pierce Wise

Abstract readReview
In one paragraph

Review in Biochemical Society transactions, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. A whale of a tale: whale cells evade the driving mechanism for hexavalent chromium-induced chromosome instability.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Article
  2. Article
  3. Chromium and genomic stability.Mutation research · 2012
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amie L HolmesWise Laboratory of Environmental and Genetic Toxicology, University of Southern Maine, 96 Falmouth Street, Portland, ME 04104, USA.
John Pierce Wise
University of Southern Maine · US

Funding

PARTICULATE CR(VI) TOXICOLOGY IN HUMAN LUNG EPITHELIAL CELLS AND FIBROBLASTS (Admin Supplement/PA-17-055)R01ES016893 · NIEHS · UNIVERSITY OF SOUTHERN MAINE · PI WISE, JOHN PIERCE · 2009 to 2021
$5.1M
NIEHS NIH HHS ES016893NIEHS NIH HHS R01 ES016893
6 · The paper itself

Abstract

Exposure to toxic and carcinogenic metals is widespread; however, their mechanisms of action remain largely unknown. One potential mechanism for metal-induced carcinogenicity and toxicity is centrosome amplification. Here we review the mechanisms for metal-induced centrosome amplification, including arsenic, chromium, mercury and nano-titanium dioxide.

Indexed as

AnimalsArsenicCarcinogensCell LineCentrosomeChromiumEnvironmental ExposureHumansMercuryNanostructuresTitaniumArsenicCarcinogensChromiumMercuryTitaniumtitanium dioxide

Identifiers

PMID21118148
PMCPMC4086844
OpenAlexW2063952014

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.