Trial reportEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2011
Outcomes differ between subgroups of patients with low back and leg pain following neural manual therapy: a prospective cohort study.
Trial report in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Hamstring Stretching and Neural Mobilization on Range of Motion and Low Back Pain
Effectiveness of Neural Mobilization Techniques Compared to Standard Care Treatment in Patients With Lumbar Radiculitis: A Randomized Clinical Trial
Neural And Hip Mobilizations In Patients With Neurogenic Claudication Associated With Degenerative Lumbar Spinal Stenosis: A Case Series
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Classification of patients with low back-related leg pain: a systematic review.BMC musculoskeletal disorders · 2016Pooled it
- [Subgroup-specific therapy of low back pain: description and validity of two classification systems].Der Orthopade · 2013Pooled it
- Trial
- [Chronic low back pain : Comparison of mobilization and core stability exercises].Der Orthopade · 2016Trial
- The pathophysiologic mechanisms of spinal manipulative therapy in the management of chronic musculoskeletal pain.The Journal of the Canadian Chiropractic Association · 2025Article
- Low-back related leg pain: is the nerve guilty? How to differentiate the underlying pain mechanism.The Journal of manual & manipulative therapy · 2023Article
- Cultural adaptation and psychometric assessment of the Persian version of the lumbar spine instability questionnaire.BMC sports science, medicine & rehabilitation · 2022Article
- [Entrapment neuropathies: a contemporary approach to pathophysiology, clinical assessment, and management : German version].Schmerz (Berlin, Germany) · 2021Review
- Application and utility of a clinical framework for spinally referred neck-arm pain: A cross-sectional and longitudinal study protocol.PloS one · 2020Article
- The effects of neurodynamic straight leg raise treatment duration on range of hip flexion and protective muscle activity at P1.The Journal of manual & manipulative therapy · 2016Article
- Clinical presentation and manual therapy for lower quadrant musculoskeletal conditions.The Journal of manual & manipulative therapy · 2011Article
- A systematic review and meta-analysis on the efficacy of physiotherapy intervention in management of lumbar prolapsed intervertebral disc.International journal of health sciencesReview
- Entrapment neuropathies: a contemporary approach to pathophysiology, clinical assessment, and management.Pain reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective is to determine if pain and disability outcomes of patients treated with neural mobilisation differ for sub-classifications of low back and leg pain (LB&LP). Radiating leg pain is a poor prognostic factor for recovery in patients with LBP. To improve outcome, a new pathomechanism-based classification system was proposed: neuropathic sensitization (NS), denervation (D), peripheral nerve sensitization (PNS) and musculoskeletal (M). Seventy-seven patients with unilateral LB&LP were recruited. Following classification, all subjects were treated seven times with neural mobilisation techniques. A successful outcome was defined as achieving a minimal clinically important change in pain intensity (11-point numerical rating scale), physical function (Roland Morris disability questionnaire) and global perceived change (7-point Likert scale: from 1 = "completely recovered" to 7 = "worse than ever"). The proportion of responders was significantly greater in PNS (55.6%) than the other three groups (NS 10%; D 14.3% and M10%). After adjusting for baseline differences, mean magnitude of improvement of the outcome measures were significantly greater in PNS compared to the other groups. Patients classified as PNS have a more favourable prognosis following neural mobilisation compared to the other groups.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.