ArticleMarine drugs2010
Effect of marine polyunsaturated fatty acids on biofilm formation of Candida albicans and Candida dubliniensis.
Article in Marine drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 62 citations in OpenAlex.
- Use of Novasomes as a Vesicular Carrier for Improving the Topical Delivery of Terconazole: In Vitro Characterization, In Vivo Assessment and Exploratory Clinical Experimentation.International journal of nanomedicine · 2021Trial
- Association of plasma n-3 polyunsaturated fatty acid with gut mycobiome and implications for glucose homeostasis.Science China. Life sciences · 2026Article
- Anti-Biofilm Extracts and Molecules from the Marine Environment.Marine drugs · 2024Review
- Surfactants' Interplay with Biofilm Development inPharmaceutics · 2024Article
- Article
- Eicosapentaenoic acid influences the pathogenesis of Candida albicans in Caenorhabditis elegans via inhibition of hyphal formation and stimulation of the host immune response.Medical microbiology and immunology · 2023Article
- A Re-Purposing Strategy: Sub-Lethal Concentrations of an Eicosanoid Derived from the Omega-3-Polyunsaturated Fatty Acid Resolvin D1 Affect Dual Species Biofilms.International journal of molecular sciences · 2023Article
- Fenticonazole nitrate loaded trans-novasomes for effective management of tinea corporis: design characterization,Drug delivery · 2022Article
- Potential inhibitory activity of phytoconstituents against black fungus:Computational toxicology (Amsterdam, Netherlands) · 2022Article
- High-throughput assay for effect screening of amphotericin B and bioactive components on filamentous Candida albicans.Journal of applied microbiology · 2022Article
- Marine Compounds with Anti-Journal of fungi (Basel, Switzerland) · 2022Review
- Article
- Review
- Antibiofilm Activity of Essential Fatty Acids AgainstInfection and drug resistance · 2022Article
- Marine Macroalgae, a Source of Natural Inhibitors of Fungal Phytopathogens.Journal of fungi (Basel, Switzerland) · 2021Review
- Antibiofilm and antifungal activities of medium-chain fatty acids against Candida albicans via mimicking of the quorum-sensing molecule farnesol.Microbial biotechnology · 2021Article
- Marine-Derived Compounds and Prospects for Their Antifungal Application.Molecules (Basel, Switzerland) · 2020Review
- Transcriptome Analyses ofG3 (Bethesda, Md.) · 2020Article
- A New Bioactive Compound From the Marine Sponge-DerivedFrontiers in microbiology · 2018Article
- Herring Oil and Omega Fatty Acids InhibitFrontiers in microbiology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effect of marine polyunsaturated fatty acids on biofilm formation by the human pathogens Candida albicans and Candida dubliniensis was investigated. It was found that stearidonic acid (18:4 n-3), eicosapentaenoic acid (20:5 n-3), docosapentaenoic acid (22:5 n-3) and docosahexaenoic acid (22:6 n-3) have an inhibitory effect on mitochondrial metabolism of both C. albicans and C. dubliniensis and that the production of biofilm biomass by C. dubliniensis was more susceptible to these fatty acids than C. albicans. Ultrastructural differences, which may be due to increased oxidative stress, were observed between treated and untreated cells of C. albicans and C. dubliniensis with formation of rough cell walls by both species and fibrillar structures in C. dubliniensis. These results indicate that marine polyunsaturated fatty acids may be useful in the treatment and/or prevention of biofilms formed by these pathogenic yeasts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.