ArticleApplied and environmental microbiology2011
Biodiversity of Clostridium botulinum type E associated with a large outbreak of botulism in wildlife from Lake Erie and Lake Ontario.
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 46 citations in OpenAlex.
- Whole genome sequencing of neurotoxin-producingFrontiers in public health · 2025Article
- Salinity tolerance of Round Goby: Informing invasion potential in North American coastal watersheds.PloS one · 2025Article
- Botulism in fish: a review.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Review
- Early-Life Fecal Transplantation from High Muscle Yield Rainbow Trout to Low Muscle Yield Recipients Accelerates Somatic Growth through Respiratory and Mitochondrial Efficiency Modulation.Microorganisms · 2024Article
- Human and animal botulism surveillance in France from 2008 to 2019.Frontiers in public health · 2022Article
- First cross-border outbreak of foodborne botulism in the European Union associated with the consumption of commercial dried roach (Frontiers in public health · 2022Article
- Review
- Differentiating Botulinum Neurotoxin-Producing Clostridia with a Simple, Multiplex PCR Assay.Applied and environmental microbiology · 2017Article
- Development and Validation of a New Reliable Method for the Diagnosis of Avian Botulism.PloS one · 2017Article
- Therapeutic management of botulism in dairy cattle.Veterinary world · 2015Article
- Clostridium botulinum Group II Isolate Phylogenomic Profiling Using Whole-Genome Sequence Data.Applied and environmental microbiology · 2015Article
- Spatial, Temporal, and Matrix Variability of Clostridium botulinum Type E Toxin Gene Distribution at Great Lakes Beaches.Applied and environmental microbiology · 2015Article
- An atypical outbreak of food-borne botulism due to Clostridium botulinum types B and E from ham.Journal of clinical microbiology · 2015Article
- Optimization of peptide substrates for botulinum neurotoxin E improves detection sensitivity in the Endopep-MS assay.Analytical biochemistry · 2015Article
- Botulism outbreaks in natural environments - an update.Frontiers in microbiology · 2014Review
- Analysis of a unique Clostridium botulinum strain from the Southern hemisphere producing a novel type E botulinum neurotoxin subtype.BMC microbiology · 2012Article
- In vitro detection and quantification of botulinum neurotoxin type e activity in avian blood.Applied and environmental microbiology · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genetic relatedness of Clostridium botulinum type E isolates associated with an outbreak of wildlife botulism was studied using random amplification of polymorphic DNA (RAPD). Specimens were collected from November 2000 to December 2008 during a large outbreak of botulism affecting birds and fish living in and around Lake Erie and Lake Ontario. In our present study, a total of 355 wildlife samples were tested for the presence of botulinum toxin and/or organisms. Type E botulinum toxin was detected in 110 samples from birds, 12 samples from fish, and 2 samples from mammals. Sediment samples from Lake Erie were also examined for the presence of C. botulinum. Fifteen of 17 sediment samples were positive for the presence of C. botulinum type E. Eighty-one C. botulinum isolates were obtained from plants, animals, and sediments; of these isolates, 44 C. botulinum isolates produced type E toxin, as determined by mouse bioassay, while the remaining 37 isolates were not toxic for mice. All toxin-producing isolates were typed by RAPD; that analysis showed 12 different RAPD types and multiple subtypes. Our study thus demonstrates that multiple genetically distinct strains of C. botulinum were involved in the present outbreak of wildlife botulism. We found that C. botulinum type E is present in the sediments of Lake Erie and that a large range of bird and fish species is affected.
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