ArticleApplied and environmental microbiology2011
Exploring the links between natural products and bacterial assemblages in the sponge Aplysina aerophoba.
Article in Applied and environmental microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 56 citations in OpenAlex.
- MALDI-FISH for Colocalization of Brominated Metabolites andJournal of natural products · 2026Article
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- Techniques for learning and transferring knowledge for microbiome-based classification and prediction: review and assessment.Briefings in bioinformatics · 2024Review
- A Study of Sponge Symbionts from Different Light Habitats.Microbial ecology · 2023Article
- PLSDA-batch: a multivariate framework to correct for batch effects in microbiome data.Briefings in bioinformatics · 2023Article
- Evaluating supervised and unsupervised background noise correction in human gut microbiome data.PLoS computational biology · 2022Article
- Roles of Organohalide-RespiringmSystems · 2020Article
- Cultivation of Bacteria FromFrontiers in microbiology · 2020Article
- Impact of the Cultivation Technique on the Production of Secondary Metabolites byMarine drugs · 2019Article
- Diversity of tryptophan halogenases in sponges of the genus Aplysina.FEMS microbiology ecology · 2019Article
- Variations in Microbial Diversity and Metabolite Profiles of the Tropical Marine Sponge Xestospongia muta with Season and Depth.Microbial ecology · 2019Article
- Bacterial Communities Inhabiting the Sponge Biemna fortis, Sediment and Water in Marine Lakes and the Open Sea.Microbial ecology · 2018Article
- Environmental heterogeneity and microbial inheritance influence sponge-associated bacterial composition of Spongia lamella.Microbial ecology · 2014Article
- Marine sponge derived natural products between 2001 and 2010: trends and opportunities for discovery of bioactives.Marine drugs · 2014Review
- Article
- Bacterial communities of the gorgonian octocoral Pseudopterogorgia elisabethae.Microbial ecology · 2013Article
- Quality or quantity: is nutrient transfer driven more by symbiont identity and productivity than by symbiont abundance?The ISME journal · 2013Article
- Trade-offs in defensive metabolite production but not ecological function in healthy and diseased sponges.Journal of chemical ecology · 2012Article
- Temporal trends in the secondary metabolite production of the sponge Aplysina aerophoba.Marine drugs · 2012Article
- Diversity and biosynthetic potential of culturable actinomycetes associated with marine sponges in the China Seas.International journal of molecular sciences · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The sponge Aplysina aerophoba produces a large diversity of brominated alkaloids (BAs) and hosts a complex microbial assemblage. Although BAs are located within sponge cells, the enzymes that bind halogen elements to organic compounds have been exclusively described in algae, fungi, and bacteria. Bacterial communities within A. aerophoba could therefore be involved in the biosynthesis of these compounds. This study investigates whether changes in both the concentration of BAs and the bacterial assemblages are correlated in A. aerophoba. To do so, we quantified major natural products using high-performance liquid chromatography and analyzed bacterial assemblages using denaturing gradient gel electrophoresis on the 16S rRNA gene. We identified multiple associations between bacteria and natural products, including a strong relationship between a Chloroflexi phylotype and aplysinamisin-1 and between an unidentified bacterium and aerophobin-2 and isofistularin-3. Our results suggest that these bacteria could either be involved in the production of BAs or be directly affected by them. To our knowledge, this is one of the first reports that find a significant correlation between natural products and bacterial populations in any benthic organism. Further investigating these associations will shed light on the organization and functioning of host-endobiont systems such as Aplysina aerophoba.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.