ArticleJournal of biological engineering2010
Bioresponsive matrices in drug delivery.
Article in Journal of biological engineering, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Long noncoding RNA MALAT1 mediates fibrous topography-driven pathologic calcification through trans-differentiation of myoblasts.Materials today. Bio · 2024Article
- Hydrogels Classification According to the Physical or Chemical Interactions and as Stimuli-Sensitive Materials.Gels (Basel, Switzerland) · 2021Review
- Synthesis and Antimicrobial Properties of Highly Cross-Linked pH-Sensitive Hydrogels through Gamma Radiation.Polymers · 2021Article
- Stimuli-Responsive Cationic Hydrogels in Drug Delivery Applications.Gels (Basel, Switzerland) · 2018Review
- Photochemically Controlled Drug Dosing from a Polymeric Scaffold.Pharmaceutical research · 2017Article
- Stimuli-Regulated Smart Polymeric Systems for Gene Therapy.Polymers · 2017Review
- A Review of Thermo- and Ultrasound-Responsive Polymeric Systems for Delivery of Chemotherapeutic Agents.Polymers · 2016Review
- ICAM-1-Targeted, Lcn2 siRNA-Encapsulating Liposomes are Potent Anti-angiogenic Agents for Triple Negative Breast Cancer.Theranostics · 2016Article
- Artificial Molecular Machines.Chemical reviews · 2015Review
- Breast Cancer: Conventional Diagnosis and Treatment Modalities and Recent Patents and Technologies.Breast cancer : basic and clinical research · 2015Review
- Pretreatment-dependent surface chemistry of wood nanocellulose for pH-sensitive hydrogels.Journal of biomaterials applications · 2014Article
- Direct Observation of Reversible Biomolecule Switching Controlled By Electrical Stimulus.Advanced materials interfaces · 2014Article
- Porphyrin-phospholipid liposomes permeabilized by near-infrared light.Nature communications · 2014Article
- Inhibiting metastatic breast cancer cell migration via the synergy of targeted, pH-triggered siRNA delivery and chemokine axis blockade.Molecular pharmaceutics · 2014Article
- Remotely triggered scaffolds for controlled release of pharmaceuticals.International journal of molecular sciences · 2013Article
- Controlled release of doxorubicin from pH-responsive microgels.Acta biomaterialia · 2013Article
- Using breast cancer cell CXCR4 surface expression to predict liposome binding and cytotoxicity.Biomaterials · 2012Article
- Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers.Journal of biological engineering · 2012Article
- Insulin analogs for the treatment of diabetes mellitus: therapeutic applications of protein engineering.Annals of the New York Academy of Sciences · 2011Article
- Enhancing Cell therapies from the Outside In: Cell Surface Engineering Using Synthetic Nanomaterials.Nano today · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For years, the field of drug delivery has focused on (1) controlling the release of a therapeutic and (2) targeting the therapeutic to a specific cell type. These research endeavors have concentrated mainly on the development of new degradable polymers and molecule-labeled drug delivery vehicles. Recent interest in biomaterials that respond to their environment have opened new methods to trigger the release of drugs and localize the therapeutic within a particular site. These novel biomaterials, usually termed "smart" or "intelligent", are able to deliver a therapeutic agent based on either environmental cues or a remote stimulus. Stimuli-responsive materials could potentially elicit a therapeutically effective dose without adverse side effects. Polymers responding to different stimuli, such as pH, light, temperature, ultrasound, magnetism, or biomolecules have been investigated as potential drug delivery vehicles. This review describes the most recent advances in "smart" drug delivery systems that respond to one or multiple stimuli.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.