Evidence map›Paper›PMID 21113775›Full record

ArticleSocial psychiatry and psychiatric epidemiology2012

Adverse effects of antipsychotic drugs: survey of doctors' versus patients' perspective.

Michela Nosè, Maria Angela Mazzi, Eleonora Esposito, Marco Bianchini, Paola Petrosemolo, Giovanni Ostuzzi, Michele Tansella, Corrado Barbui

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Article in Social psychiatry and psychiatric epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michela NosèDepartment of Public Health and Community Medicine, Section of Psychiatry and Clinical Psychology, University of Verona, Policlinico GB Rossi, 37134 Verona, Italy. michela.nose@univr.it
Maria Angela Mazzi
Eleonora Esposito
Marco Bianchini
Paola Petrosemolo
Giovanni Ostuzzi
Michele Tansella
Corrado Barbui

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAlmost no data are available on whether patients and doctors have similar or dissimilar opinions on the presence and level of distress due to antipsychotic adverse effects. The aim of this survey is to compare doctors' versus patients' perspective on the presence and level of distress due to antipsychotic adverse effects in a sample of patients under the care of the South-Verona mental health services.

methodsAll patients exposed to antipsychotic drugs during a census period of 6 months were identified. For each included subject, socio-demographic, clinical and treatment data were extracted. Patients' perspective on antipsychotic adverse effects was measured by means of the Liverpool University Neuroleptic Side Effect Rating Scale (LUNSERS). The LUNSERS was similarly employed to measure doctors' perspective on antipsychotic adverse effects.

resultsDuring the recruitment period, 243 patients taking antipsychotic drugs were enrolled. The correlation between the total LUNSERS score reported by patients and doctors was very low (correlation coefficient 0.22, 95% confidence interval 0.15-0.30). On average, patients perceived more adverse effects and with a significant higher distress than doctors. Multivariate analyses found no factors simultaneously associated with both patient and doctor ratings of adverse effects.

conclusionOur study suggests that doctors, researchers and health care providers should increasingly consider patient and doctor perspectives as two complementary dimensions that may provide different insights in the evaluation of antipsychotic drugs. Integrating different points of view may represent a way to develop a better therapeutic alliance that might decrease the likelihood of nonadherence.

Indexed as

Attitude of Health PersonnelAttitude to HealthPhysiciansAdultAntipsychotic AgentsCommunity Mental Health ServicesData CollectionFemaleHumansItalyMaleMiddle AgedPhysician-Patient RelationsYoung AdultAntipsychotic Agents

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