Evidence map›Paper›PMID 21113651›Full record

ArticleJournal of fluorescence2011

Folate conjugated CdHgTe quantum dots with high targeting affinity and sensitivity for in vivo early tumor diagnosis.

Haiyan Chen, Li Li, Sisi Cui, Dider Mahounga, Jun Zhang, Yueqing Gu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 24 citations in OpenAlex.

  1. Development andNanomedicine (London, England) · 2025
    Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Haiyan ChenDepartment of Biomedical Engineering, School of Life Science and Technology, China Pharmaceutical University, 24 Tongjia Lane, Gulou District, Nanjing 210009, China.
Li Li
Sisi Cui
Dider Mahounga
Jun Zhang
Yueqing Gu
China Pharmaceutical University · CNXinxiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CdHgTe-folate conjugates, acting as novel active-targeting fluorescence probes, were prepared by covalent conjugation of CdHgTe QDs and folic acid. Their characteristics, such as optical spectra, stability and cancer cell targeting were investigated in detail. The fluorescence wavelength of CdHgTe-folate conjugates was 790 nm and a full width at half-maximum (FWHM) of them was 50-70 nm. Their fluorescence stability could satisfy the need of long and continuous fluorescence imaging. The in vivo dynamic bio-distribution of CdHgTe-folate conjugates in S180 tumor beard mouse model was monitored by a NIR imaging system. The resultes indicated that CdHgTe-folate conjugates targeted to tumor effectively. The high fluorescence intensity together with targeting effect makes CdHgTe-folate conjugates promising candidates for imaging, monitoring and early diagnosis of cancer at molecular and cell level.

Indexed as

Quantum DotsAbsorptionAnimalsCadmium CompoundsCarbodiimidesCarcinosarcomaEarly Detection of CancerFluorescent DyesFolic AcidHeLa CellsHumansMercury CompoundsMiceMolecular ImagingOptical PhenomenaSensitivity and Specificity1-ethyl-3-(3-dimethylaminoisopropyl) carbodiimideCadmium CompoundsCarbodiimidesFluorescent DyesFolic Acidmercury cadmium tellurideMercury CompoundsN-hydroxysulfosuccinimideSuccinimides

Identifiers

PMID21113651
OpenAlexW2016487646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.