ArticleBiophysical journal2010
Squeezing and detachment of living cells.
Article in Biophysical journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Forces and symmetry breaking of a living meso-swimmer.Communications physics · 2026Article
- Soft matter mechanics of immune cell aggregates.Journal of the Royal Society, Interface · 2025Article
- Dynamic force measurements on swimmingJournal of the Royal Society, Interface · 2020Article
- The Effect of Cortical Elasticity and Active Tension on Cell Adhesion Mechanics.Biophysical journal · 2019Article
- Micropipette force sensors for in vivo force measurements on single cells and multicellular microorganisms.Nature protocols · 2019Article
- The nematode C. elegans as a complex viscoelastic fluid.The European physical journal. E, Soft matter · 2015Article
- Direct measurements of drag forces in C. elegans crawling locomotion.Biophysical journal · 2014Article
- Tumor cohesion and glioblastoma cell dispersal.Future oncology (London, England) · 2013Article
- Viscoelastic properties of the nematode Caenorhabditis elegans, a self-similar, shear-thinning worm.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The interaction of living cells with their environment is linked to their adhesive and elastic properties. Even if the mechanics of simple lipid membranes is fairly well understood, the analysis of single cell experiments remains challenging in part because of the mechanosensory response of cells to their environment. To study the mechanical properties of living cells we have developed a tool that borrows from micropipette aspiration techniques, atomic force microscopy, and the classical Johnson-Kendall-Roberts test. We show results from a study of the adhesion properties of living cells, as well as the elastic response and relaxation. We present models that are applied throughout the different stages of an experiment, which indicate that the contribution of the different components of the cell are active at various stages of compression, retraction, and detachment. Finally, we present a model that attempts to elucidate the surprising logarithmic relaxation observed when the cell is subjected to a given deformation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.