Evidence map›Paper›PMID 21111227›Full record

ArticleCell2010

Glycomics hits the big time.

Gerald W Hart, Ronald J Copeland

Open access · bronzeAbstract read
In one paragraph

Article in Cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 266 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
266citing papers in PubMed, 1 pooled it
14.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

266 citing papers in PubMed, 1 synthesis or guideline pooled it, 634 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  6. Article
  7. Review
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  12. Article
  13. The Intersection of Glycosylation and Ferroptosis in Cancer.Antioxidants (Basel, Switzerland) · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. O-GlcNAc informatics: advances and trends.Analytical and bioanalytical chemistry · 2025
    Review

206 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gerald W HartDepartment of Biological Chemistry, Johns Hopkins University, Baltimore, MD 21205-2185, USA. gwhart@jhmi.edu
Ronald J Copeland
Johns Hopkins University · US

Funding

JHU-UMD Diabetes Research CenterP30DK079637 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI WONDISFORD, FREDRIC E. · 2013 to 2017
$9.7M
ROLE OF CELL-SURFACE SIALYLATION IN TUMOR METASTASISR01CA042486 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI HART, GERALD WARREN · 1986 to 2013
$4.9M
Cytosolic O-Glycosylation and Insulin SignalingR01DK061671 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HART, GERALD WARREN · 2002 to 2014
$4.0M
O-GlcNAc:Developing New Tool for Assessment of GlycemiaR33DK071280 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HART, GERALD WARREN · 2007 to 2008
$913k
Mechanisms of Glucose ToxicityR24DK084949 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI HART, GERALD WARREN, HOKE, AHMET · 2010 to 2010
$492k
NCI NIH HHS R01 CA042486NCI NIH HHS R01CA42486NIDDK NIH HHS P30 DK079637NIDDK NIH HHS R01 DK061671NIDDK NIH HHS R01DK61671NIDDK NIH HHS R24 DK084949NIDDK NIH HHS R33 DK071280
6 · The paper itself

Abstract

Cells run on carbohydrates. Glycans, sequences of carbohydrates conjugated to proteins and lipids, are arguably the most abundant and structurally diverse class of molecules in nature. Recent advances in glycomics reveal the scope and scale of their functional roles and their impact on human disease.

Indexed as

GlycomicsAnimalsBiomarkers, TumorGlycolipidsGlycosylationGlycosyltransferasesHumansNeoplasmsPolysaccharidesProtein Processing, Post-TranslationalProteoglycansBiomarkers, TumorGlycolipidsGlycosyltransferasesPolysaccharidesProteoglycans

Identifiers

PMID21111227
PMCPMC3008369
OpenAlexW2068339549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.