Evidence map›Paper›PMID 21110060›Full record

ArticleInternational journal of public health2011

A generally applicable cost-effectiveness model for the evaluation of vaccines against cervical cancer.

Nadia Demarteau, Bruno Detournay, Bertrand Tehard, Abdelkader El Hasnaoui, Baudouin Standaert

Open access · hybridAbstract read
In one paragraph

Article in International journal of public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  7. Article
  8. Review
  9. Applying a Simple Model of Cost Effectiveness Study of HPV Vaccine for Iran.Iranian journal of pharmaceutical research : IJPR · 2015
    Article
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  12. Article
  13. Review
  14. Article
  15. Present challenges in cervical cancer prevention: Answers from cost-effectiveness analyses.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Nadia DemarteauHealth Economics, GlaxoSmithKline Biologicals, Wavre, Belgium. nadia.x.demarteau@gskbio.com
Bruno Detournay
Bertrand Tehard
Abdelkader El Hasnaoui
Baudouin Standaert
GlaxoSmithKline (Belgium) · BEGlaxoSmithKline (United Kingdom) · GBCemka-Eval (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed at evaluating the cost-effectiveness of human papillomavirus virus (HPV) vaccination in France, using a generally applicable succinct cohort model.

methodsA lifetime Markov cohort model, adapted to the French setting, simulate the natural history of oncogenic HPV infection towards cervical cancer (CC). Additional modules account for the effects of screening and vaccination. The girls' cohort is vaccinated at age 12 and follows current screening. Costs and outcomes (discounted at 3 and 1.5%, respectively) were compared with a cohort receiving screening alone.

resultsThe model results agreed well with real-life data. Vaccination in addition to screening would substantially reduce the incidence of and mortality from CC, compared with screening alone, at an estimated cost-effectiveness of <euro>9,706 per quality-adjusted-life-year. Sensitivity analysis showed that the discount rate and the parameters related to the disease history have the largest impact on the results.

conclusionThis succinct cohort model indicated that HPV vaccination would be a cost-effective policy option in France. It uses readily available data and should be generally applicable to the evaluation of HPV vaccination in a variety of countries and settings.

Indexed as

ChildCohort StudiesCost-Benefit AnalysisFemaleFranceHumansIncidenceMarkov ChainsModels, EconometricPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsVaccinationPapillomavirus Vaccines

Identifiers

PMID21110060
PMCPMC3066388
OpenAlexW2068219907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.