Evidence map›Paper›PMID 21109412›Full record

ReviewCurrent opinion in immunology2010

The role of thymic stromal lymphopoietin (TSLP) in allergic disorders.

Steven F Ziegler

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
19.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 153 citations in OpenAlex.

  1. A phenotypically and functionally distinct human TScience translational medicine · 2017
    Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. EoE behaves as a unique Th2 disease: a narrative review.Translational gastroenterology and hepatology · 2023
    Review
  8. TSLP, IL-33, and IL-25: Not just for allergy and helminth infection.The Journal of allergy and clinical immunology · 2022
    Review
  9. Epigenetic Mechanisms of Epidermal Differentiation.International journal of molecular sciences · 2022
    Review
  10. Article
  11. Review
  12. Journal of ginseng research · 2021
    Article
  13. Review
  14. Review
  15. Nasal Epithelial Cells Activated withInternational journal of molecular sciences · 2020
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Steven F ZieglerImmunology Program, Benaroya Research Institute, Seattle, WA 98101, United States. sziegler@benaroyaresearch.org
Benteler (Czechia) · CZ

Funding

TSLP and the Pathophysiology of AsthmaR01AI068731 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI ZIEGLER, STEVEN F · 2006 to 2016
$4.5M
TSLP receptor in the regulation of cell developmentR01AI044259 · NIAID · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI ZIEGLER, STEVEN F · 1999 to 2010
$2.5M
Regulation of TSLP-Mediated Skin InflammationR01AR055695 · NIAMS · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI CAMPBELL, DANIEL J, HAMERMAN, JESSICA A · 2009 to 2013
$2.0M
TSLP and Contact HypersensitivityR01AR056113 · NIAMS · BENAROYA RESEARCH INST AT VIRGINIA MASON · PI ZIEGLER, STEVEN F · 2008 to 2012
$2.0M
NIAID NIH HHS R01 AI044259NIAID NIH HHS R01 AI068731NIAMS NIH HHS R01 AR055695NIAMS NIH HHS R01 AR056113
6 · The paper itself

Abstract

The importance of the epithelium in initiating and controlling immune responses is becoming more appreciated. For example, allergen contact first occurs at mucosal sites exposed to the external environment, such as the skin, airways and gastrointestinal tract. This exposure leads to the production of a variety of cytokines and chemokines that are involved in driving allergic inflammatory responses. One such product is thymic stromal lymphopoietin (TSLP). Recent studies, in both humans and mouse models, have implicated TSLP in the development and progression of atopy and atopic diseases. This review will discuss this work and place TSLP in the inflammatory cascade that leads to allergic disease.

Indexed as

AnimalsCytokinesHumansHypersensitivityThymic Stromal LymphopoietinCytokinesThymic Stromal Lymphopoietin

Identifiers

PMID21109412
PMCPMC3032269
OpenAlexW2107256985

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.