ArticleJournal of affective disorders2011
Depression and eating disorders: treatment and course.
Article in Journal of affective disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 137 citations in OpenAlex.
- The prevalence of feeding and eating disorders symptomology in medical students: an updated systematic review, meta-analysis, and meta-regression.Eating and weight disorders : EWD · 2022Pooled it
- A randomized, controlled pilot study of positive affect treatment adapted for anorexia nervosa.The International journal of eating disorders · 2024Trial
- Posttraumatic stress disorder in African Americans: a two year follow-up study.Psychiatry research · 2014Trial
- Developing a Clinical Prediction Model for Nonimprovement of Depressive Symptoms at Discharge After Treatment of Eating Disorders.The International journal of eating disorders · 2026Article
- Effects of Dog-assisted Therapy in Anxiety Symptoms of Female Adolescents With Eating Disorders: A Controlled Trial.Actas espanolas de psiquiatria · 2025Article
- Exploring the Interplay Between Thyroid Hormone Levels and Symptoms of Anxiety and Depression in Anorexia Nervosa.Brain and behavior · 2025Article
- Anxiety, Obsessive-Compulsive, and Depressive Symptom Presentation and Change Throughout Routine Eating Disorder Treatment.European eating disorders review : the journal of the Eating Disorders Association · 2025Article
- Mediating role of exercise in the relationship between body dissatisfaction and overeating using structural equation modeling.BMC public health · 2025Article
- Body image, eating distress and emotional-behavioral difficulties among adolescents in Mbarara, Southwestern Uganda.BMC public health · 2024Article
- An Umbrella Review and a Meta-analysis of Meta-analyses of Disordered Eating Among Medical Students.Alpha psychiatry · 2024Review
- Modeling the relationship between depression in people with cancer and perceived stress, with the mediating role of eating problems, sexual satisfaction, emotion regulation and self-compassion.Frontiers in psychology · 2024Article
- Comparison among anorexia nervosa adolescents with or without previous overweight, obese, and healthy adolescents.Frontiers in psychiatry · 2024Article
- The paradoxical moderating effects of metacognition in the relationships between self-esteem, depressive symptoms, and quality of life in anorexia and bulimia.Consortium psychiatricum · 2023Article
- Eating disorder patients with and without PTSD treated in residential care: discharge and 6-month follow-up results.Journal of eating disorders · 2023Article
- Article
- Analysis of Electrolyte Abnormalities in Adolescents and Adults and Subsequent Diagnosis of an Eating Disorder.JAMA network open · 2022Article
- Mediation models of anxiety and depression between temperament and drive for thinness and body dissatisfaction in anorexia nervosa.Eating and weight disorders : EWD · 2022Article
- Broad and Narrow Transdiagnostic Risk Factors in Eating Disorders: A Preliminary Study on an Italian Clinical Sample.International journal of environmental research and public health · 2022Article
- In pursuit of biomarkers for predicting susceptibility to activity-based anorexia in adolescent female rats.The International journal of eating disorders · 2022Article
- Biological, psychological and familial specific correlates in eating disorders at onset: a control-case study protocol (ANOBAS).Actas espanolas de psiquiatria · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundWe examined the course of major depressive disorder (MDD) and predictors of MDD recovery and relapse in a longitudinal sample of women with eating disorders (ED).
methods246 Boston-area women with DSM-IV anorexia nervosa-restricting (ANR; n=51), AN-binge/purge (ANBP; n=85), and bulimia nervosa (BN; n=110) were recruited between 1987 and 1991 and interviewed using the Eating Disorders Longitudinal Interval Follow-up Evaluation (LIFE-EAT-II) every 6-12 months for up to 12 years. 100 participants had MDD at study intake and 45 developed MDD during the study. Psychological functioning and treatment were assessed.
resultsTimes to MDD onset (1 week-4.3 years), recovery (8 weeks-8.7 years), and relapse (1 week-5.2 years) varied. 70% recovered from MDD, but 65% subsequently relapsed. ANR patients were significantly less likely to recover from MDD than ANBP patients (p=0.029). Better psychological functioning and history of MDD were associated with higher chance of MDD recovery. Higher baseline depressive severity and full recovery from ED were associated with greater likelihood of MDD relapse; increased weight loss was somewhat protective. Adequate antidepressant treatment was given to 72% of patients with MDD and generally continued after MDD recovery. Time on antidepressants did not predict MDD recovery (p=0.27) or relapse (p=0.26). LIMITATIONS: Small ED diagnostic subgroups; lack of non-ED control group.
conclusionsThe course of MDD in EDs is protracted; MDD recovery may depend on ED type. Antidepressants did not impact likelihood of MDD recovery, nor protect against relapse, which may impact on treatment strategies for comorbid MDD and EDs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.