ArticleJournal of medical virology2011
Respiratory viruses in children admitted to hospital intensive care units: evaluating the CLART® Pneumovir DNA array.
Article in Journal of medical virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- The role of viral co-infections in the severity of acute respiratory infections among children infected with respiratory syncytial virus (RSV): A systematic review and meta-analysis.Journal of global health · 2020Pooled it
- Multiplex PCR system for the rapid diagnosis of respiratory virus infection: systematic review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018Pooled it
- Respiratory viral coinfection and disease severity in children: A systematic review and meta-analysis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Pooled it
- The prevalence and role of human respiratory syncytial virus in pediatric respiratory tract infections: a systematic review and meta-analysis of global data.EClinicalMedicine · 2026Article
- Ambulance dispatch calls attributable to influenza A and other common respiratory viruses in the Netherlands (2014-2016).Influenza and other respiratory viruses · 2020Article
- The molecular epidemiology of respiratory viruses in military trainees in Iran.Medical journal of the Islamic Republic of Iran · 2019Article
- Multiplex PCR reveals that viruses are more frequent than bacteria in children with cystic fibrosis.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2017Article
- Benefits and drawbacks of molecular techniques for diagnosis of viral respiratory infections. Experience with two multiplex PCR assays.Journal of medical virology · 2016Article
- Comparison of the performance of 2 commercial multiplex PCR platforms for detection of respiratory viruses in upper and lower tract respiratory specimens.Diagnostic microbiology and infectious disease · 2015Article
- The clinical and etiological characteristics of influenza-like illness (ILI) in outpatients in Shanghai, China, 2011 to 2013.PloS one · 2015Article
- Article
- Viral coinfection in childhood respiratory tract infections.Archivos de bronconeumologia · 2015Article
- Viral etiology of influenza-like illnesses in Huizhou, China, from 2011 to 2013.Archives of virology · 2014Article
- Detection of Herpesviridae in whole blood by multiplex PCR DNA-based microarray analysis after hematopoietic stem cell transplantation.Journal of clinical microbiology · 2014Article
- Microarray multiplex assay for the simultaneous detection and discrimination of influenza a and influenza B viruses.Indian journal of microbiology · 2014Article
- A DNA microarray-based assay to detect dual infection with two dengue virus serotypes.Sensors (Basel, Switzerland) · 2014Article
- Respiratory viruses associated with patients older than 50 years presenting with ILI in Senegal, 2009 to 2011.BMC infectious diseases · 2014Observational
- Evaluation of viral co-infections in hospitalized and non-hospitalized children with respiratory infections using microarrays.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2013Article
- Comparative evaluation of six commercialized multiplex PCR kits for the diagnosis of respiratory infections.PloS one · 2013Article
- The microarray technology: facts and controversies.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Viruses play a significant part in children's respiratory infections, sometimes leading to hospitalization in cases of severe respiratory distress. The aim of this study was to investigate respiratory infections in children treated in a hospital intensive care unit (ICU). Assays were performed using the CLART® Pneumovir DNA array assay (Genomica, Coslada, Madrid, Spain), which makes it possible to detect 11 genus of respiratory viruses simultaneously. During the winter of 2008-2009, 73 respiratory specimens collected from 53 children under 2 years of age and admitted to an ICU were tested. At least one virus was detected in 78% (57/73) of the samples. The virological diagnosis was based on single infections in 65% (37/57) and on multiple infections in 35% (20/57) of cases. The array assay revealed respiratory syncytial virus (RSV) in 73.6% (42/57) of the samples and rhinovirus in 24.6% (14/57), either on their own or in co-infections. All viruses identified in single and multiple infections were tested, taking into account clinical features, risk factors, and severity criteria. Children with no risk factors presented more multiple infections, up to 42% of cases, than children with at least one risk factor. RSV seemed to induce severe symptoms by itself as no difference in intubation needs was observed when RSV was detected on its own or in co-infection. The CLART® Pneumovir DNA array was useful for examining severe viral respiratory infections, when other viruses than those detected by conventional methods could be involved, particularly in an ICU.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.