ArticleJournal of assisted reproduction and genetics2011
Pronuclear embryo cryopreservation experience: outcomes for reducing the risk of ovarian hyperstimulation syndrome and for fertility preservation in cancer patients.
Article in Journal of assisted reproduction and genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Outcomes after assisted reproductive technology in women with cancer: a systematic review and meta-analysis.Human reproduction (Oxford, England) · 2023Pooled it
- Live birth rate after use of cryopreserved oocytes or embryos at the time of cancer diagnosis in female survivors: a retrospective study of ten years of experience.Journal of assisted reproduction and genetics · 2021Article
- Counseling young women with early breast cancer on fertility preservation.Journal of assisted reproduction and genetics · 2019Article
- Fertility preservation from the point of view of hematopoietic cell transplant specialists-a worldwide-web-based survey analysis.Bone marrow transplantation · 2019Article
- Thirteen years' experience in fertility preservation for cancer patients after in vitro fertilization and in vitro maturation treatments.Journal of assisted reproduction and genetics · 2018Article
- Responses to fertility treatment among patients with cancer: a retrospective cohort study.Fertility research and practice · 2018Article
- Utilization rates and results of long-term embryo cryopreservation before gonadotoxic treatment.Journal of assisted reproduction and genetics · 2015Article
- Ovarian stimulation and in-vitro fertilization outcomes of cancer patients undergoing fertility preservation compared to age matched controls: a 17-year experience.Journal of assisted reproduction and genetics · 2015Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate pregnancy rate (PR) and live birth rate (LBR) after freezing pronuclear (PN) embryos for two purposes: to reduce the risk of ovarian hyperstimulation syndrome (OHSS) and to bank embryos for cancer patients anticipating gametotoxic chemotherapy/radiotherapy.
methodsData from 3,621 consecutive IVF cycles were retrospectively analyzed. PN freezing was offered to patients at risk for OHSS and for those wishing to preserve fertility prior to cancer therapy. Primary outcomes evaluated were PR and LBR. Outcomes were compared to patients who underwent fresh embryo transfer (ET) in 2006.
resultsSixty-six patients froze PN embryos. Thirty-eight were at risk for OHSS. The LBR was 34.3% after one transfer, and 51.4% after a mean of 1.4 transfers. Twenty-eight cancer patients froze embryos. The LBR was 16.7% after one transfer and 25.0% after a mean of 1.5 transfers. The LBR was 35.5% for patients who underwent fresh ET.
conclusionPN freezing with delayed ET is an effective tool for achieving pregnancy for patients at risk of OHSS and for cancer patients wishing to preserve fertility.
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Registered trials
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