ArticleInternational journal of colorectal disease2011
Management and outcome of colorectal anastomotic leaks.
Article in International journal of colorectal disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06273826 (The Implementation of the Mobile Application "Colorectal Leakage App", Based on the Dutch Leakage Score, for Early Detection of Anastomotic Leakage After Colorectal Surgeries), which is not on this map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Implementation of the Mobile Application "Colorectal Leakage App", Based on the Dutch Leakage Score, for Early Detection of Anastomotic Leakage After Colorectal Surgeries
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Management of anastomotic leak after elective anterior resection for rectal cancer: A systematic review and pooled analysis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Pooled it
- C-reactive protein can predict anastomotic leak in colorectal surgery: a systematic review and meta-analysis.International journal of colorectal disease · 2021Pooled it
- External coating of colonic anastomoses: a systematic review.International journal of colorectal disease · 2012Pooled it
- Does ghost ileostomy have a role in the laparoscopic rectal surgery era? A randomized controlled trial.Surgical endoscopy · 2015Trial
- Endoscopic management of colocolonic anastomotic dehiscence: a case report.iGIE : innovation, investigation and insights · 2026Article
- No significant association between perioperative serum sodium and intestinal anastomotic leaks: a systematic review and meta-analysis.Surgery in practice and science · 2026Review
- Management of anastomotic leak following restorative rectal cancer resection-a multi-centre retrospective audit in Ireland.Irish journal of medical science · 2026Article
- Understanding Anastomotic Healing in Colo-Rectal Surgery; a Multicentric 5-Year Analysis of Predictive Factors for Integrity and Fistula Formation.Diagnostics (Basel, Switzerland) · 2026Article
- Real-Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Anastomotic Leak Following Colorectal Surgery.Clinics in colon and rectal surgery · 2026Review
- Improved outcomes with cyanoacrylate glue for ileocolic anastomosis in right colectomy: a multicenter study.Annals of coloproctology · 2025Article
- Biophysical modeling and artificial intelligence for quantitative assessment of anastomotic blood supply in laparoscopic low anterior rectal resection.Surgical endoscopy · 2025Article
- Implementation of intraoperative procedures to prevent anastomotic leak in low anterior rectal resections: a pilot study for a novel technique to evaluate anastomotic vascularization.Surgical endoscopy · 2025Article
- The implementation of the mobile application "Colorectal Leakage App", based on the Dutch Leakage Score, for early detection of anastomotic leakage after colorectal surgeries-pilot study.Frontiers in surgery · 2025Article
- Article
- The mesenteric entry site as a potential weak point in gastrointestinal anastomoses - findings from an ex-vivo biomechanical analysis.Langenbeck's archives of surgery · 2024Article
- Article
- What affects the selection of diverting ileostomy in rectal cancer surgery: a single-center retrospective study.BMC surgery · 2024Article
- Outcomes following anastomotic leak from rectal resections, including bowel function and quality of life.Annals of coloproctology · 2023Article
- Impact of anastomotic leakage on long-term prognosis after colorectal cancer surgery.World journal of gastrointestinal surgery · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAnastomotic leak is a devastating complication of an intestinal anastomosis. Optimal management and outcome is not routinely described, and much of our knowledge relies upon historical data. We wished to examine the management and outcome of anastomotic leaks on a colorectal surgery unit in the twenty-first century.
methodA retrospective audit of all patients who had a colorectal anastomotic leak between January 2002 and December 2008 in a large university teaching hospital. Data collected included patient characteristics, primary diagnosis, mode of diagnosis and time to diagnosis of anastomotic leak, inpatient management, morbidity and mortality, permanent stoma rate, use of hospital resources.
resultsThirty patients (16 male, 14 female), with a median age of 60 years (range 25-84 years), had an anastomotic leak. The median time to presentation of clinically suspected leaks was 12 days (range 3-56 days). Fourteen patients required reoperation, with ten needing the anastomosis take down. Average hospital stay was 40 days. The permanent stoma rate following a rectal anastomotic leak was 27% and 57.1% from a colonic leak. Overall mortality in this series was 27%. Mortality was higher after leak from a colonic anastomosis than after leak from a rectal anastomosis (43.8% vs. 7.1%, respectively).
conclusionsAnastomotic leaks are not detected until late in the post-operative period and are associated with a high mortality. Demand on hospital resources is high. In this series, patients who leaked after a colonic anastomosis had a higher mortality and permanent stoma rate than after leaks from a rectal anastomosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.