ArticleInternational urogynecology journal2011
In vitro and in vivo assessment of silver-coated polypropylene mesh to prevent infection in a rat model.
Article in International urogynecology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Pooled it
- HPMC-ZnO Nanorods Enhance Hydrophilicity and Contact-Killing Activity on Polypropylene Meshes and Sutures.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Analysis of polypropylene meshes with embedded silver ions in ventral hernia repair: can they be used in different grades of contamination?Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Abdominal wall hernia repair: from prosthetic meshes to smart materials.Materials today. Bio · 2023Review
- Non-destructive processing of silver containing glass ceramic antibacterial coating on polymeric surgical mesh surfaces.Nanoscale · 2023Article
- Antimicrobial Meshes for Hernia Repair: Current Progress and Perspectives.Journal of clinical medicine · 2022Review
- Tannic acid-loaded hydrogel coating endues polypropylene mesh with hemostatic and anti-inflammatory capacity for facilitating pelvic floor repair.Regenerative biomaterials · 2022Article
- Bioinspired Hydrogel Coating Based on Methacryloyl Gelatin Bioactivates Polypropylene Meshes for Abdominal Wall Repair.Polymers · 2020Article
- Complications related to use of mesh implants in surgical treatment of stress urinary incontinence and pelvic organ prolapse: infection or inflammation?World journal of urology · 2020Review
- A critical review of the in vitro and in vivo models for the evaluation of anti-infective meshes.Hernia : the journal of hernias and abdominal wall surgery · 2018Review
- In vivo response to polypropylene following implantation in animal models: a review of biocompatibility.International urogynecology journal · 2017Review
- Design Strategies and Applications of Biomaterials and Devices for Hernia Repair.Bioactive materials · 2016Article
- Polypropylene surgical mesh coated with extracellular matrix mitigates the host foreign body response.Journal of biomedical materials research. Part A · 2014Article
- Mesh biocompatibility: effects of cellular inflammation and tissue remodelling.Langenbeck's archives of surgery · 2012Review
- Basic science and clinical aspects of mesh infection in pelvic floor reconstructive surgery.International urogynecology journal · 2011Review
- New strategies to improve results of mesh surgeries for vaginal prolapses repair--an update.International braz j urol : official journal of the Brazilian Society of UrologyReview
- Effect of platelet-rich plasma on polypropylene meshes implanted in the rabbit vagina: histological analysis.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThe purpose of this study is to determine the effect of silver coating of polypropylene implants on infection in hernia surgery.
methodsSilver-coated and non-silver-coated large pore monofilament polypropylene mesh implants were compared with and without infection (four groups). The implants were inserted in the abdominal wall of female Wistar rats. An Escherichia coli strain was inoculated intraoperatively in the two infected groups. The implants were removed, and clinical, bacteriological, and histological analyses were performed at 2, 15, and 30 days postoperatively.
resultsEighty-four rats were studied. All inoculated rats (n = 21) in the non-silver-coated polypropylene group presented periprosthetic E. coli infection, compared with only five inoculated rats in the silver-coated polypropylene group (p < 0.0001). Erosion was significantly higher in the infected than in the non-infected silver-coated polypropylene groups (p < 0.01). There was no histological difference between the four groups.
conclusionsSilver-coated implants appear effective against bacterial infection in our rat model, with good histological tolerance but delayed healing.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.