SynthesisBMC public health2010
The Early Prevention of Obesity in CHildren (EPOCH) Collaboration--an individual patient data prospective meta-analysis.
Synthesis in BMC public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Examining the sustainability of effects of early childhood obesity prevention interventions: Follow-up of the EPOCH individual participant data prospective meta-analysis.Pediatric obesity · 2022Pooled it
- Pooled it
- Bidirectional associations between mothers' feeding practices and child eating behaviours.The international journal of behavioral nutrition and physical activity · 2018Trial
- A 3-Arm randomised controlled trial of Communicating Healthy Beginnings Advice by Telephone (CHAT) to mothers with infants to prevent childhood obesity.BMC public health · 2017Trial
- Three-year follow-up of a randomised controlled trial to reduce excessive weight gain in the first two years of life: protocol for the POI follow-up study.BMC public health · 2016Trial
- The extended Infant Feeding, Activity and Nutrition Trial (InFANT Extend) Program: a cluster-randomized controlled trial of an early intervention to prevent childhood obesity.BMC public health · 2016Trial
- Using the Medical Research Council framework for the development and evaluation of complex interventions in a theory-based infant feeding intervention to prevent childhood obesity: the baby milk intervention and trial.Journal of obesity · 2014Trial
- The double task of preventing malnutrition and overweight: a quasi-experimental community-based trial.BMC public health · 2013Trial
- Prevention of Overweight in Infancy (POI.nz) study: a randomised controlled trial of sleep, food and activity interventions for preventing overweight from birth.BMC public health · 2011Trial
- The Association Between the Early Introduction of Solid Food and Childhood Obesity Risk: A Systematic Review.Cureus · 2025Review
- Infancy Dietary Patterns, Development, and Health: An Extensive Narrative Review.Children (Basel, Switzerland) · 2022Review
- Article
- Bedtime, body mass index and obesity risk in preschool-aged children.Pediatric obesity · 2020Article
- Associations between childhood overweight, obesity, abdominal obesity and obesogenic behaviors and practices in Australian homes.BMC public health · 2017Article
- Assessing User Engagement of an mHealth Intervention: Development and Implementation of the Growing Healthy App Engagement Index.JMIR mHealth and uHealth · 2017Article
- The Effect of Early Life Factors and Early Interventions on Childhood Overweight and Obesity 2016.Journal of obesity · 2017Article
- Mothers' feeding behaviors in infancy: Do they predict child weight trajectories?Obesity (Silver Spring, Md.) · 2015Article
- Article
- Protocol for systematic reviews of determinants/correlates of obesity-related dietary and physical activity behaviors in young children (preschool 0 to 6 years): evidence mapping and syntheses.Systematic reviews · 2013Article
- Recruiting and engaging new mothers in nutrition research studies: lessons from the Australian NOURISH randomised controlled trial.The international journal of behavioral nutrition and physical activity · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEfforts to prevent the development of overweight and obesity have increasingly focused early in the life course as we recognise that both metabolic and behavioural patterns are often established within the first few years of life. Randomised controlled trials (RCTs) of interventions are even more powerful when, with forethought, they are synthesised into an individual patient data (IPD) prospective meta-analysis (PMA). An IPD PMA is a unique research design where several trials are identified for inclusion in an analysis before any of the individual trial results become known and the data are provided for each randomised patient. This methodology minimises the publication and selection bias often associated with a retrospective meta-analysis by allowing hypotheses, analysis methods and selection criteria to be specified a priori. METHODS/
designThe Early Prevention of Obesity in CHildren (EPOCH) Collaboration was formed in 2009. The main objective of the EPOCH Collaboration is to determine if early intervention for childhood obesity impacts on body mass index (BMI) z scores at age 18-24 months. Additional research questions will focus on whether early intervention has an impact on children's dietary quality, TV viewing time, duration of breastfeeding and parenting styles. This protocol includes the hypotheses, inclusion criteria and outcome measures to be used in the IPD PMA. The sample size of the combined dataset at final outcome assessment (approximately 1800 infants) will allow greater precision when exploring differences in the effect of early intervention with respect to pre-specified participant- and intervention-level characteristics. DISCUSSION: Finalisation of the data collection procedures and analysis plans will be complete by the end of 2010. Data collection and analysis will occur during 2011-2012 and results should be available by 2013. TRIAL REGISTRATION NUMBER: ACTRN12610000789066.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.