Evidence map›Paper›PMID 21105146›Full record

ReviewJournal of magnetic resonance imaging : JMRI2010

Image-based modeling of lung structure and function.

Merryn H Tawhai, Ching-Long Lin

Abstract readReview
In one paragraph

Review in Journal of magnetic resonance imaging : JMRI, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Forward Computational Modeling of Respiratory Airflow.Applied sciences (Basel, Switzerland) · 2024
    Article
  3. Digital twins for chronic lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. A Review of Respiratory Anatomical Development, Air Flow Characterization and Particle Deposition.International journal of environmental research and public health · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Merryn H TawhaiAuckland Bioengineering Institute, University of Auckland, Auckland, New Zealand. m.tawhai@auckland.ac.nz
Ching-Long Lin

Funding

UNIVERSITY OF IOWA CTSA FOR PEDIATRIC RESEARCHUL1RR024979 · NCRR · UNIVERSITY OF IOWA · PI ROSENTHAL, GARY E · 2007 to 2011
$31.8M
Image and Model Based Analysis of Lung DiseasesR01HL064368 · NHLBI · UNIVERSITY OF IOWA · PI HOFFMAN, ERIC ALFRED · 1999 to 2009
$15.6M
Multiscale Interaction of Pulmonary Gas Flow and Lung Tissue MechanicsR01HL094315 · NHLBI · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2010 to 2013
$1.4M
MSM simulation of gas flow distribution in human lungR01EB005823 · NIBIB · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2005 to 2007
$894k
Large-Scale Computing and Visualization for Cardiopulmonary ImagingS10RR022421 · NCRR · UNIVERSITY OF IOWA · PI LIN, CHING-LONG · 2008 to 2008
$474k
NCRR NIH HHS 1UL1RR024979NCRR NIH HHS S10 RR022421NCRR NIH HHS S10-RR-022421NCRR NIH HHS UL1 RR024979NHLBI NIH HHS R01 HL064368NHLBI NIH HHS R01-HL064368NHLBI NIH HHS R01 HL094315NHLBI NIH HHS R01-HL094315NIBIB NIH HHS R01 EB005823NIBIB NIH HHS R01-EB005823
6 · The paper itself

Abstract

The current state-of-the-art in image-based modeling allows derivation of patient-specific models of the lung, lobes, airways, and pulmonary vascular trees. The application of traditional engineering analyses of fluid and structural mechanics to image-based subject-specific models has the potential to provide new insight into structure-function relationships in the individual via functional interpretation that complements imaging and experimental studies. Three major issues that are encountered in studies of airflow through the bronchial airways are the representation of airway geometry, the imposition of physiological boundary conditions, and the treatment of turbulence. Here we review some efforts to resolve each of these issues, with particular focus on image-based models that have been developed to simulate airflow from the mouth to the terminal bronchiole, and subjected to physiologically meaningful boundary conditions via image registration and soft-tissue mechanics models.

Indexed as

BronchiolesDiagnostic ImagingHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLungModels, BiologicalPulmonary VentilationRespirationRespiratory Mechanics

Identifiers

PMID21105146
PMCPMC3058528

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.