ArticleIrish journal of medical science2011
Dynamic changes of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) on pulmonary injury induced by ischemia-reperfusion in rats.
Article in Irish journal of medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Immune response associated with ischemia and reperfusion injury during organ transplantation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022Review
- LncRNA np_5318 promotes renal ischemia-reperfusion injury through the TGF-β/Smad signaling pathway.Experimental and therapeutic medicine · 2020Article
- Ischemia and reperfusion injury in superficial inferior epigastric artery-based vascularized lymph node flaps.PloS one · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
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Abstract
objectiveTo evaluate the dynamic changes of PECAM-1/CD31 on pulmonary injury induced by ischemia-reperfusion (IR) in rats.
methodsAn isolated lung ischemia in rats was performed for 60 min, followed separately by 0, 2, 4, 6 or 8 h for reperfusion. At the end of reperfusion, the expression of PECAM-1/CD31 was detected by using flow cytometry (FCM). Simultaneously, we examined the ultrastructure changes of cells by transmission electron microscope.
resultsThe expressions of PECAM-1/CD31 in neutrophils and lymphocytes of the blood were increased after IR; the peak was at 2 h after IR, then the expressions were gradually decreased to control level at 6 and 8 h after IR. Ultrastructural morphological changes including proliferation of alveolar type II and apoptotic bodies were seen after IR, the most prominently at 2 h after IR.
conclusionPECAM-1/CD31 is involved in the pulmonary injury induced by IR.
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