ReviewJournal of cardiovascular translational research2011
Cardiovascular implications in the treatment of obstructive sleep apnea.
Review in Journal of cardiovascular translational research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- The Use of Remotely Controlled Mandibular Positioner as a Predictive Screening Tool for Mandibular Advancement Device Therapy in Patients with Obstructive Sleep Apnea through Single-Night Progressive Titration of the Mandible: A Systematic Review.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2016Pooled it
- Effects of steam-assisted respiratory muscle training on sleep apnoea symptoms and pulmonary function in men and women: a pilot study.Sleep & breathing = Schlaf & Atmung · 2025Trial
- Functional imaging improves patient selection for mandibular advancement device treatment outcome in sleep-disordered breathing: a prospective study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Mandibular advancement device treatment and reverse left ventricular hypertrophic remodeling in patients with obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022Trial
- Can we enhance compliance to treatment by performing a continuous positive airway pressure trial in obstructive sleep apnea?Sleep & breathing = Schlaf & Atmung · 2021Trial
- Treatment of obstructive sleep apnea using a custom-made titratable duobloc oral appliance: a prospective clinical study.Sleep & breathing = Schlaf & Atmung · 2013Trial
- Site of Collapse during Drug-induced Sleep Endoscopy Is Associated with Polysomnographic Endotypic Traits: An Observational Study.Annals of the American Thoracic Society · 2025Observational
- The Baveno Classification as a Predictor of CPAP Titration Pressure in Obstructive Sleep Apnea Syndrome.Advances in respiratory medicine · 2023Article
- Obstructive sleep apnea and cardiovascular disease, a story of confounders!Sleep & breathing = Schlaf & Atmung · 2020Review
- The Effect of Obstructive Sleep Apnea on Absolute Risk of Central Serous Chorioretinopathy.American journal of ophthalmology · 2020Article
- Obstructive sleep apnea and hypertension in pediatric chronic kidney disease.Pediatric nephrology (Berlin, Germany) · 2019Observational
- Strategies in the clinical diagnosis and surgical treatment of OSAHS with multilevel obstruction.The Journal of international medical research · 2019Article
- The predictive value of drug-induced sleep endoscopy for CPAP titration in OSA patients.Sleep & breathing = Schlaf & Atmung · 2018Article
- Serum ferritin and obstructive sleep apnea-epidemiological study.Sleep & breathing = Schlaf & Atmung · 2018Article
- The long-term effects of mandibular advancement splint on cardiovascular fitness and psychomotor performance in patients with mild to moderate obstructive sleep apnea: a prospective study.Sleep & breathing = Schlaf & Atmung · 2017Article
- Prevalence and clinical significance of supine-dependent obstructive sleep apnea in patients using oral appliance therapy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2014Article
- Is insulin the new intermittent hypoxia?Medical hypotheses · 2014Article
- Evaluation of the impact of a clinical pathway on the organization of a multidisciplinary dental sleep clinic.Sleep & breathing = Schlaf & Atmung · 2014Article
- Retention of mandibular advancement devices in the treatment of obstructive sleep apnea: an in vitro pilot study.Sleep & breathing = Schlaf & Atmung · 2014Article
- Central and peripheral factors contributing to obstructive sleep apneas.Respiratory physiology & neurobiology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epidemiological studies provide strong evidence that obstructive sleep apnea (OSA) is associated with cardiovascular complications such as systemic hypertension, congestive heart failure, and atrial fibrillation. Successful OSA treatment with continuous positive airway pressure (CPAP) has resulted in coincident reductions in systemic hypertension, improvements in left ventricular systolic function, and reductions in sympathetic nervous activity. These data suggest that successful treatment of OSA may reduce cardiovascular morbidity in such patients. Although CPAP is the more successful treatment for OSA when used properly and consistently, its clinical success is often limited by poor patient and partner acceptance, which leads to suboptimal compliance. Oral appliances or upper airway surgeries are considered a second line of treatment for patients with mild to moderate OSA who do not comply with or refuse long-term CPAP treatment. Oral devices such as mandibular repositioning appliances were recently shown to improve arterial hypertension in OSA patients. Electrical stimulation of the hypoglossal nerve is a new investigational therapy for patients with moderate to severe OSA. This new treatment option, if proven effective, may provide cardiovascular benefits secondary to treating OSA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.