Evidence map›Paper›PMID 21099596›Full record

Trial reportObstetrics and gynecology2010

Home compared with clinic-based screening for sexually transmitted infections: a randomized controlled trial.

Anna S Graseck, Gina M Secura, Jenifer E Allsworth, Tessa Madden, Jeffrey F Peipert

3 registry-linked trialsAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Obstetrics and gynecology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01184157 nacompletednot on this map

Randomized Trial of Home Versus Clinic-based Screening for Sexually Transmitted Infections in Long-Acting Reversible Contraceptive Users

TypeinterventionalSponsorWashington University School of MedicineConditionsChlamydia, GonorrheaArmsHome screening, Clinic screening
NCT01654991 nacompletednot on this map

A Randomized Trial of Home Versus Clinic-Based STD Testing Among Men

TypeinterventionalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2010 to 2011Enrolled200ConditionsChlamydia, GonorrheaArmsHome Screening, Clinic Screening
NCT01986439 unknown statusnot on this map

The Contraceptive Choice Project

TypeobservationalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2007 to 2016Enrolled9,256ConditionsUnintended Pregnancy, Teen Births, Abortion, Contraception
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Screening for genital chlamydia infection.The Cochrane database of systematic reviews · 2016
    Review
  12. Article
  13. Journal of clinical outcomes management : JCOM · 2014
    Article
  14. Article
  15. Article
  16. Article
  17. Factors associated with screening for sexually transmitted infections.American journal of obstetrics and gynecology · 2012
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna S GraseckFrom the Division of Clinical Research, Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Gina M Secura
Jenifer E Allsworth
Tessa Madden
Jeffrey F Peipert

Funding

Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational Sciences (KL2)KL2RR024994 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$8.6M
Washington University Institute of Clinical and Translational Sciences (TL1)TL1RR024995 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$2.3M
MIDCAREER INVESTIGATOR AWARD IN WOMEN'S HEALTH RESEARCHK24HD001298 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI PEIPERT, JEFFREY FRANK · 2000 to 2009
$1.1M
NCRR NIH HHS KL2 RR024994NCRR NIH HHS KL2RR024994NCRR NIH HHS TL1 RR024995NCRR NIH HHS UL1 RR024992NCRR NIH HHS UL1RR024992NICHD NIH HHS K24 HD001298NICHD NIH HHS K24 HD01298PHS HHS K3054628
6 · The paper itself

Abstract

objectiveTo determine whether home-based screening for sexually transmitted infections results in a higher sexually transmitted infection screening rate compared with clinic-based screening in participants using long-acting reversible contraception.

methodsWe performed a randomized clinical trial of women using long-acting reversible contraception methods in the Contraceptive CHOICE Project (n=558). Participants were randomly assigned to home-based testing (swabs mailed to the participant's home) or clinic-based testing. Self-collected vaginal swabs were tested for Chlamydia trachomatis and Neisseria gonorrhoeae using strand displacement analysis. We estimated the relative risk (RR) of screening by group using Poisson regression with robust error variance.

resultsThe randomization groups were similar at baseline, except for marital status; the clinic group had more never-married women (62.0% compared with 51.6%), and the home group had more divorced women (12.1% compared with 5.6%, P=.007). Women in the home group were more likely to self-report screening compared with women in the clinic group in the multivariable analysis (56.3% compared with 32.9%; RR 1.7; 95% confidence interval [CI] 1.4-2.0). When analyzed by tests received or documented in medical records, similar results were obtained (56.3% compared with 25.0%; RR 2.2; 95% CI 1.7-2.7). Women who completed screening had higher levels of education and were more likely to receive public assistance compared with those who did not complete screening.

conclusionLong-acting reversible contraception users randomized to sexually transmitted infection screening at home were more likely to complete screening than those randomized to traditional clinic-based screening. Home-based screening may be useful in women using long-acting reversible contraceptive methods who may not present for regular screening. CLINICAL

trial registrationClinicalTrials.gov, www.clinicaltrials.gov, NCT01184157.

Indexed as

Chlamydia trachomatisCommunity Health CentersSelf CareChlamydia InfectionsFemaleGonorrheaHumansPatient ComplianceReagent Kits, DiagnosticSexually Transmitted DiseasesReagent Kits, Diagnostic

Identifiers

PMID21099596
PMCPMC3120128

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.