Evidence map›Paper›PMID 21099592›Full record

ArticleObstetrics and gynecology2010

Contemporary patterns of spontaneous labor with normal neonatal outcomes.

Jun Zhang, Helain J Landy, D Ware Branch, Ronald Burkman, Shoshana Haberman, Kimberly D Gregory, Christos G Hatjis, Mildred M Ramirez, Jennifer L Bailit, Victor H Gonzalez-Quintero and 8 more

3 registry-linked trialsAbstract readMulticenter Study
In one paragraph

Article in Obstetrics and gynecology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 207 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
207citing papers in PubMed, 6 pooled it
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05579808 completednot on this mapstarted 2021, after this paper: background citation

The Effect of Epidural Analgesia on Labour and Neonatal and Maternal Outcomes in 1, 2a, 3, and 4a Robson's Classes: a Propensity Score-matched Analysis

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2021 to 2021Enrolled21,808ConditionsLabor Pain, Delivery Complication, Regional Anesthesia MorbidityArmsEpidural Analgesia
NCT05906303 phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Caffeine in the Second Stage: A Randomized Control Trial in Low-risk Nulliparous Mothers at Term

TypeinterventionalSponsorThe Reading Hospital and Medical CenterRan2023 to 2025Enrolled80ConditionsSecond Stage of LaborArmsCaffeine and Sodium Benzoate Injection, Normal Saline
NCT06987591 completednot on this mapstarted 2023, after this paper: background citation

Impact of Low-Dose Epidural Analgesia on Labour Progression in Robson Class 1 Women: a Retrospective Study

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2023 to 2025Enrolled5,995ConditionsEpidural Analgesia, Obstetric
3 · Its place in the literature

Who cites it

207 citing papers in PubMed, 6 syntheses or guidelines pooled it, 781 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Duration of spontaneous labour in 'low-risk' women with 'normal' perinatal outcomes: A systematic review.European journal of obstetrics, gynecology, and reproductive biology · 2018
    Pooled it
  5. Guideline
  6. Pooled it
  7. Trial
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  13. Foley catheter for induction of labor: potential barriers to adopting the technique.Journal of perinatology : official journal of the California Perinatal Association · 2015
    Trial
  14. Article
  15. Article
  16. Article
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  18. Article
  19. An Appraisal of Labor Augmentation: An Update on Current Evidence and Practice.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2026
    Review
  20. Time of day of induction impacts the total duration of labor.American journal of obstetrics & gynecology MFM · 2026
    Article

147 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Jun ZhangFrom the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland; Georgetown University Hospital, MedStar Health, Washington, DC; Intermountain HealthCare and University of Utah, Salt Lake City, Utah; Baystate Medical Center, Springfield, Massachusetts; Maimonides Medical Center, Brooklyn, New York; Cedars-Sinai Medical Center, Los Angeles, California; Summa Health System, Akron City Hospital, Akron, Ohio; University of Texas Health Science Center at Houston, Houston, Texas; MetroHealth Medical Center, Cleveland, Ohio; University of Miami, Miami, Florida; University of Illinois at Chicago, Chicago, Illinois; Christiana Care Health System, Wilmington, Delaware; Indiana University-Clarian Health, Indianapolis, Indiana; and The EMMES Corporation, Rockville, Maryland.
Helain J Landy
D Ware Branch
Ronald Burkman
Shoshana Haberman
Kimberly D Gregory
Christos G Hatjis
Mildred M Ramirez
Jennifer L Bailit
Victor H Gonzalez-Quintero
Judith U Hibbard
Matthew K Hoffman
Michelle Kominiarek
Lee A Learman
Paul Van Veldhuisen
James Troendle
Uma M Reddy
Consortium on Safe Labor
Georgetown University · US

Funding

Intramural NIH HHSNICHD NIH HHS HHSN267200603425CNIDDK NIH HHS HHSN267200603425C
6 · The paper itself

Abstract

objectiveTo use contemporary labor data to examine the labor patterns in a large, modern obstetric population in the United States.

methodsData were from the Consortium on Safe Labor, a multicenter retrospective study that abstracted detailed labor and delivery information from electronic medical records in 19 hospitals across the United States. A total of 62,415 parturients were selected who had a singleton term gestation, spontaneous onset of labor, vertex presentation, vaginal delivery, and a normal perinatal outcome. A repeated-measures analysis was used to construct average labor curves by parity. An interval-censored regression was used to estimate duration of labor, stratified by cervical dilation at admission and centimeter by centimeter.

resultsLabor may take more than 6 hours to progress from 4 to 5 cm and more than 3 hours to progress from 5 to 6 cm of dilation. Nulliparous and multiparous women appeared to progress at a similar pace before 6 cm. However, after 6 cm, labor accelerated much faster in multiparous than in nulliparous women. The 95 percentiles of the second stage of labor in nulliparous women with and without epidural analgesia were 3.6 and 2.8 hours, respectively. A partogram for nulliparous women is proposed.

conclusionIn a large, contemporary population, the rate of cervical dilation accelerated after 6 cm, and progress from 4 cm to 6 cm was far slower than previously described. Allowing labor to continue for a longer period before 6 cm of cervical dilation may reduce the rate of intrapartum and subsequent repeat cesarean deliveries in the United States.

Indexed as

Labor, ObstetricFemaleHumansInfant, NewbornLabor Stage, FirstLabor Stage, SecondParityPregnancyPregnancy OutcomeReference Values

Identifiers

PMID21099592
PMCPMC3660040
OpenAlexW2118727855

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.