Evidence map›Paper›PMID 21098097›Full record

ReviewThe Journal of experimental medicine2010

Networking erythropoiesis.

Marc A Kerenyi, Stuart H Orkin

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of experimental medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multi-lineage Differentiation from Hematopoietic Stem Cells.Advances in experimental medicine and biology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marc A KerenyiDivision of Hematology/Oncology, Children's Hospital Boston and the Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.
Stuart H Orkin
Dana-Farber Cancer Institute · USHarvard University · US

Funding

MOLECULAR ANALYSIS OF NORMAL AND TYHALASSEMIC DNAR01HL032259 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI ORKIN, STUART H · 1985 to 2022
$8.8M
Howard Hughes Medical InstituteNHLBI NIH HHS R01 HL032259
6 · The paper itself

Abstract

A relatively small cadre of lineage-restricted transcription factors largely orchestrates erythropoiesis, but how these nuclear factors interact to regulate this complex biology is still largely unknown. However, recent technological advances, such as chromatin immunoprecipitation (ChIP) paired with massively parallel sequencing (ChIP-seq), gene expression profiling, and comprehensive bioinformatic analyses, offer new insights into the intricacies of red cell molecular circuits.

Indexed as

ErythropoiesisAnimalsBasic Helix-Loop-Helix ProteinsChromatin ImmunoprecipitationComputational BiologyGATA1 Transcription FactorGene Expression ProfilingHumansKruppel-Like Transcription FactorsProto-Oncogene ProteinsT-Cell Acute Lymphocytic Leukemia Protein 1Transcription FactorsBasic Helix-Loop-Helix Proteinserythroid Kruppel-like factorGATA1 Transcription FactorKruppel-Like Transcription FactorsProto-Oncogene ProteinsTAL1 protein, humanT-Cell Acute Lymphocytic Leukemia Protein 1Transcription Factors

Identifiers

PMID21098097
PMCPMC2989762
OpenAlexW4230746892

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.