ArticleNucleic acids research2011
Extending CATH: increasing coverage of the protein structure universe and linking structure with function.
Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
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Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Rifampin phosphotransferase is an unusual antibiotic resistance kinase.Nature communications · 2016Article
- Impact of structure space continuity on protein fold classification.Scientific reports · 2016Article
- Similarity in Shape Dictates Signature Intrinsic Dynamics Despite No Functional Conservation in TIM Barrel Enzymes.PLoS computational biology · 2016Article
- DOMMINO 2.0: integrating structurally resolved protein-, RNA-, and DNA-mediated macromolecular interactions.Database : the journal of biological databases and curation · 2016Article
- The language of the protein universe.Current opinion in genetics & development · 2015Review
- The value of protein structure classification information-Surveying the scientific literature.Proteins · 2015Article
- An assessment of the amount of untapped fold level novelty in under-sampled areas of the tree of life.Scientific reports · 2015Article
- Modularity of Protein Folds as a Tool for Template-Free Modeling of Structures.PLoS computational biology · 2015Article
- The enzymatic nature of an anonymous protein sequence cannot reliably be inferred from superfamily level structural information alone.Protein science : a publication of the Protein Society · 2015Article
- Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Chemical Society reviews · 2015Review
- Alteration of substrate specificity of alanine dehydrogenase.Protein engineering, design & selection : PEDS · 2015Article
- CFam: a chemical families database based on iterative selection of functional seeds and seed-directed compound clustering.Nucleic acids research · 2015Article
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- Integrated visual analysis of protein structures, sequences, and feature data.BMC bioinformatics · 2015Article
- The InterPro protein families database: the classification resource after 15 years.Nucleic acids research · 2015Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
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Abstract
CATH version 3.3 (class, architecture, topology, homology) contains 128,688 domains, 2386 homologous superfamilies and 1233 fold groups, and reflects a major focus on classifying structural genomics (SG) structures and transmembrane proteins, both of which are likely to add structural novelty to the database and therefore increase the coverage of protein fold space within CATH. For CATH version 3.4 we have significantly improved the presentation of sequence information and associated functional information for CATH superfamilies. The CATH superfamily pages now reflect both the functional and structural diversity within the superfamily and include structural alignments of close and distant relatives within the superfamily, annotated with functional information and details of conserved residues. A significantly more efficient search function for CATH has been established by implementing the search server Solr (http://lucene.apache.org/solr/). The CATH v3.4 webpages have been built using the Catalyst web framework.
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