ArticleJournal of bacteriology2011
African 2, a clonal complex of Mycobacterium bovis epidemiologically important in East Africa.
Article in Journal of bacteriology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Burden and Genetic Diversity of Mycobacterium bovis Infection in Humans in the Middle East and North Africa: A Systematic Review and Meta-Analysis.Transboundary and emerging diseases · 2026Pooled it
- Antimicrobial peptides for tuberculosis in a post-antibiotic era: from in vitro promise to therapeutic potential.npj antimicrobials and resistance · 2026Review
- First isolation of Mycobacterium tuberculosis from suspected cases of bovine tuberculosis in rural abattoirs in Chad.Tropical animal health and production · 2026Article
- Insight into the genetic diversity ofMicrobiology spectrum · 2026Article
- Phylogenetic analysis of Mycobacterium bovis reveals animal and zoonotic tuberculosis spread between Morocco and European countries.PLoS neglected tropical diseases · 2025Article
- Bovine tuberculosis in cattle slaughtered at Addis Ababa abattoir in Ethiopia and workforce awareness of zoonotic risk.PloS one · 2025Article
- Enhanced analysis of the genomic diversity ofFrontiers in microbiology · 2025Article
- Zoonotic transmission of theFrontiers in veterinary science · 2025Article
- Genetic diversities and drug resistance in Mycobacterium bovis isolates from zoonotic tuberculosis using whole genome sequencing.BMC genomics · 2024Article
- First Insight into the Whole Genome Sequencing Whole Variations inMicroorganisms · 2024Article
- InsideFrontiers in microbiology · 2024Article
- Review
- Features ofMicroorganisms · 2023Article
- Spoligotype analysis ofZoonoses and public health · 2022Article
- Molecular epidemiology of bovine tuberculosis in Northern Ghana identifies several uncharacterized bovine spoligotypes and suggests possible zoonotic transmission.PLoS neglected tropical diseases · 2022Article
- Spatial distribution of Mycobacterium bovis spoligotypes in cattle from the state of Minas Gerais, Brazil.Tropical animal health and production · 2022Article
- SITVITBovis-a publicly available database and mapping tool to get an improved overview of animal and human cases caused by Mycobacterium bovis.Database : the journal of biological databases and curation · 2022Article
- Selective sweep sites and SNP dense regions differentiateFrontiers in microbiology · 2022Article
- Inferring Mycobacterium bovis transmission between cattle and badgers using isolates from the Randomised Badger Culling Trial.PLoS pathogens · 2021Article
- Bacteriological and molecular characterization of Mycobacterium bovis isolates from tuberculous lesions collected among slaughtered cattle, Northwest Ethiopia.BMC microbiology · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
35 authors.
Funding
Abstract
We have identified a clonal complex of Mycobacterium bovis isolated at high frequency from cattle in Uganda, Burundi, Tanzania, and Ethiopia. We have named this related group of M. bovis strains the African 2 (Af2) clonal complex of M. bovis. Af2 strains are defined by a specific chromosomal deletion (RDAf2) and can be identified by the absence of spacers 3 to 7 in their spoligotype patterns. Deletion analysis of M. bovis isolates from Algeria, Mali, Chad, Nigeria, Cameroon, South Africa, and Mozambique did not identify any strains of the Af2 clonal complex, suggesting that this clonal complex of M. bovis is localized in East Africa. The specific spoligotype pattern of the Af2 clonal complex was rarely identified among isolates from outside Africa, and the few isolates that were found and tested were intact at the RDAf2 locus. We conclude that the Af2 clonal complex is localized to cattle in East Africa. We found that strains of the Af2 clonal complex of M. bovis have, in general, four or more copies of the insertion sequence IS6110, in contrast to the majority of M. bovis strains isolated from cattle, which are thought to carry only one or a few copies.
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