ArticleChemistry & biology2010
Assembling ligands in situ using bioorthogonal boronate ester synthesis.
Article in Chemistry & biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Synergistic Effects of Polycationic and Polyfluorinated Functionalities for Efficient Intracellular Protein Delivery.Biomacromolecules · 2025Article
- A melanin-like polymer bearing phenylboronic units as a suitable bioplatform for living cell display technology.Scientific reports · 2024Article
- Recent developments in the medicinal chemistry of single boron atom-containing compounds.Acta pharmaceutica Sinica. B · 2021Review
- Boronic acid based dynamic click chemistry: recent advances and emergent applications.Chemical science · 2020Review
- Controlled Supramolecular Assembly Inside Living Cells by Sequential Multistaged Chemical Reactions.Journal of the American Chemical Society · 2020Article
- In Situ Formation of Polymeric Nanoassemblies Using an Efficient Reversible Click Reaction.Angewandte Chemie (International ed. in English) · 2020Article
- Zinc induced structural changes in the intrinsically disordered BDNF Met prodomain confer synaptic elimination.Metallomics : integrated biometal science · 2020Article
- Reversible Click Chemistry for Ultrafast and Quantitative Formation of Protein-Polymer Nanoassembly and Intracellular Protein Delivery.ACS nano · 2019Article
- Synaptogenesis Stimulates a Proteasome-Mediated Ribosome Reduction in Axons.Cell reports · 2019Article
- PROneurotrophins and CONSequences.Molecular neurobiology · 2018Review
- Mesenchymal stem cells secretome-induced axonal outgrowth is mediated by BDNF.Scientific reports · 2017Article
- The proteasome controls presynaptic differentiation through modulation of an on-site pool of polyubiquitinated conjugates.The Journal of cell biology · 2016Article
- Article
- Boron chemicals in diagnosis and therapeutics.Future medicinal chemistry · 2013Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Many molecules that could manipulate cellular function are not practical due to their large size and concomitant undesirable pharmocokinetic properties. Here, we describe a bioorthogonal, highly stable boronate ester (HiSBE) synthesis and use this reaction to synthesize a biologically active molecule from smaller precursors in a physiological context. The rapid rate of HiSBE synthesis suggests that it may be useful for assembling a wide variety of biologically active molecules in physiological solutions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.