ReviewClinics in plastic surgery2011
Pathogenesis of vascular anomalies.
Review in Clinics in plastic surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Preliminary results of the European multicentric phase III trial regarding sirolimus in slow-flow vascular malformations.JCI insight · 2023Trial
- Insights Into Congenital Lymphatic Anomalies Underlying Fetal Effusions.Prenatal diagnosis · 2026Article
- Giant hepatic hemangioma in a Japanese adult patient reduced by sirolimus therapy.Clinical journal of gastroenterology · 2025Article
- Vascular lesions: Hemangioma or venous malformation?Radiology case reports · 2025Article
- Biological identity of orbital cavernous venous malformations.Arquivos brasileiros de oftalmologia · 2024Review
- Whole mount of adult ear skin as a model to study vascular malformations.Animal models and experimental medicine · 2023Article
- Direct stick embolization of a rectal venous malformation via transanal minimally invasive surgery.Journal of vascular surgery cases and innovative techniques · 2023Article
- Osler-Weber-Rendu syndrome: A case report on a rare vascular malformation presented with lower gastrointestinal bleeding.Clinical case reports · 2023Article
- Article
- Intralesional diode laser pretreatment facilitates surgery for orbital venous malformations: initial experience with 23 consecutive patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
- A literature review of microvascular proliferation in arteriovenous malformations of skin and soft tissue.Journal of clinical and translational research · 2021Review
- Central nervous system vascular malformations: A clinical review.Annals of clinical and translational neurology · 2021Review
- A frog in my throat doctor, well perhaps a tadpole? An interesting case of a laryngeal arteriovenous malformation.BMJ case reports · 2020Article
- Blue rubber bleb nevus syndrome in a Malay girl: A case report and literature review.International journal of surgery case reports · 2020Article
- A multi-disciplinary, multimodal approach for the management of vascular anomalies.Pakistan journal of medical sciences · 2020Article
- Comprehensive molecular and clinicopathological analysis of vascular malformations: A study of 319 cases.Genes, chromosomes & cancer · 2019Article
- Cellular and molecular mechanisms of PIK3CA-related vascular anomalies.Vascular biology (Bristol, England) · 2019Review
- Sirolimus is efficacious in treatment for extensive and/or complex slow-flow vascular malformations: a monocentric prospective phase II study.Orphanet journal of rare diseases · 2018Article
- Combined Lymphedema and Capillary Malformation of the Lower Extremity.Plastic and reconstructive surgery. Global open · 2016Article
- Facial and Scalp Swelling in the Pediatric Population With Hemophilia: A Diagnosis Pitfall.Eplasty · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Vascular anomalies are localized defects of vascular development. Most of them occur sporadically (ie, there is no familial history of lesions, yet in a few cases clear inheritance is observed). These inherited forms are often characterized by multifocal lesions that are mainly small in size and increase in number with patients' age. The authors review the known (genetic) causes of vascular anomalies and call attention to the concept of Knudson's double-hit mechanism to explain incomplete penetrance and large clinical variation in expressivity observed in inherited vascular anomalies. The authors also discuss the identified pathophysiological pathways involved in vascular anomalies and how it has opened the doors toward a more refined classification of vascular anomalies and the development of animal models that can be tested for specific molecular therapies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.