Evidence map›Paper›PMID 21095231›Full record

ArticleNeuroImage2011

Speech-induced suppression of evoked auditory fields in children who stutter.

Deryk S Beal, Maher A Quraan, Douglas O Cheyne, Margot J Taylor, Vincent L Gracco, Luc F De Nil

Registry-linked trialAbstract read
In one paragraph

Article in NeuroImage, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07215884 (Dopamine and Sensorimotor Function in Stuttering), which is not on this map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07215884 phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Dopamine and Sensorimotor Function in Stuttering

TypeinterventionalSponsorUniversity of California, San FranciscoRan2025 to 2027Enrolled25ConditionsStuttering, AdultArmsAripiprazole 10 MG, Placebo
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 79 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Weak Vestibular Response in Persistent Developmental Stuttering.Frontiers in integrative neuroscience · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Functional and Neuroanatomical Bases of Developmental Stuttering: Current Insights.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2019
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Cortical activity during cued picture naming predicts individual differences in stuttering frequency.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Deryk S BealDepartment of Speech-Language Pathology, University of Toronto, Toronto, Ontario, Canada. d.beal@utoronto.ca
Maher A Quraan
Douglas O Cheyne
Margot J Taylor
Vincent L Gracco
Luc F De Nil
Hospital for Sick Children · CAUniversity of Toronto · CAMcGill University · CA

Funding

Neural control and sensorimotor mechanisms in stutteringR01DC007603 · NIDCD · UNIVERSITY OF WASHINGTON · PI MAX, LUDO · 2006 to 2010
$1.9M
CIHR MOP-68969NIDCD NIH HHS R01 DC007603NIDCD NIH HHS R01-DC-007603
6 · The paper itself

Abstract

Auditory responses to speech sounds that are self-initiated are suppressed compared to responses to the same speech sounds during passive listening. This phenomenon is referred to as speech-induced suppression, a potentially important feedback-mediated speech-motor control process. In an earlier study, we found that both adults who do and do not stutter demonstrated a reduced amplitude of the auditory M50 and M100 responses to speech during active production relative to passive listening. It is unknown if auditory responses to self-initiated speech-motor acts are suppressed in children or if the phenomenon differs between children who do and do not stutter. As stuttering is a developmental speech disorder, examining speech-induced suppression in children may identify possible neural differences underlying stuttering close to its time of onset. We used magnetoencephalography to determine the presence of speech-induced suppression in children and to characterize the properties of speech-induced suppression in children who stutter. We examined the auditory M50 as this was the earliest robust response reproducible across our child participants and the most likely to reflect a motor-to-auditory relation. Both children who do and do not stutter demonstrated speech-induced suppression of the auditory M50. However, children who stutter had a delayed auditory M50 peak latency to vowel sounds compared to children who do not stutter indicating a possible deficiency in their ability to efficiently integrate auditory speech information for the purpose of establishing neural representations of speech sounds.

Indexed as

Brain MappingBrainChildEvoked Potentials, AuditoryHumansMagnetic Resonance ImagingMagnetoencephalographyMaleSpeechStuttering

Identifiers

PMID21095231
PMCPMC3042852
OpenAlexW1992919705

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.