ReviewImmunology and allergy clinics of North America2011
Epidemiology of stress and asthma: from constricting communities and fragile families to epigenetics.
Review in Immunology and allergy clinics of North America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02206750 (The Interaction of Social Factors With Air Pollution), which is not on this map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Interaction of Social Factors With Air Pollution
Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Are prenatal anxiety or depression symptoms associated with asthma or atopic diseases throughout the offspring's childhood? An updated systematic review and meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Pooled it
- Predicting asthma prevalence across US communities by integrating social vulnerability and environmental risk with machine learning.The Journal of allergy and clinical immunology · 2026Article
- Maternal Prenatal Psychosocial Stress in Relation to Maternal and Neonatal Anemia.Current developments in nutrition · 2026Article
- Exploring the causal link between childhood maltreatment and asthma: a Mendelian randomization study.European journal of psychotraumatology · 2025Article
- Longitudinally investigating patterns of maternal psychological distress in a South African birth cohort.BMC public health · 2025Article
- Asthma: Biomedical and Psychobiological Perspectives.Biopsychosocial science and medicine · 2025Review
- Oxytocin-Mediate Modulation of Splenic Immunosuppression in Chronic Social Stress Through Neuroendocrine Pathways.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- SCD and asthma comorbidity: the potential role of adverse childhood experiences.Journal of sickle cell disease · 2025Article
- Creating home-based pulmonary rehabilitation programs for patients with asthma: insights from practice.Journal of Yeungnam medical science · 2025Article
- Review
- The Stress Phenotyping Framework: A multidisciplinary biobehavioral approach for assessing and therapeutically targeting maladaptive stress physiology.Stress (Amsterdam, Netherlands) · 2024Review
- Ozone Pollution, Perceived Support at Home, and Asthma Symptom Severity in the Adolescent Sample of the California Health Interview Survey.International journal of behavioral medicine · 2023Article
- Impact of Unmet Social Needs, Scarcity, and Future Discounting on Adherence to Treatment in Children With Asthma: Protocol for a Prospective Cohort Study.JMIR research protocols · 2023Article
- Development and Pilot Randomized Trial of a Coping Skills Intervention for Low-SES Latinx Families of Children with Asthma.Clinical practice in pediatric psychology · 2022Article
- Resting-State Functional Connectivity of the Central Executive Network Moderates the Relationship Between Neighborhood Violence and Proinflammatory Phenotype in Children.Biological psychiatry · 2021Article
- Cockroach exposure and perceived stress interact to predict clinical outcomes in childhood asthma.BMC pulmonary medicine · 2021Article
- Risk and protective factors for child development: An observational South African birth cohort.PLoS medicine · 2019Observational
- The relationship between caregivers' subjective social status and asthma symptoms and management for urban children.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019Article
- Maternal psychosocial risk factors and lower respiratory tract infection (LRTI) during infancy in a South African birth cohort.PloS one · 2019Article
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
Several epidemiologic frameworks, exemplified through extant research examples, provide insight into the role of stress in the expression of asthma and other allergic disorders. Biologic, psychological, and social processes interact throughout the life course to influence disease expression. Studies exploiting a child development framework focus on critical periods of exposure, including the in utero environment, to examine the influence of stress on disease onset. Early stress effects that alter the normal course of morphogenesis and maturation that affect both structure and function of key organ systems (eg, immune, respiratory) may persist into adult life underscoring the importance of a life course perspective. Other evidence suggests that maternal stress influences programming of integrated physiologic systems in their offspring (eg, neuroendocrine, autonomic, immune function) starting in pregnancy; consequently stress effects may be transgenerational. A multilevel approach that includes an ecological perspective may help to explain heterogeneities in asthma expression across socioeconomic and geographic boundaries that to date remain largely unexplained. Evolving studies incorporating psychological, behavioral, and physiologic correlates of stress more specifically inform underlying mechanisms operating in these critical periods of development. The role of genetics, gene by environment interactions, and epigenetic mechanisms of gene expression have been sparsely examined in epidemiologic studies on stress and asthma although overlapping evidence provides proof of concept for such studies in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.