Evidence map›Paper›PMID 21094184›Full record

ReviewThe Journal of infection2011

The role of particle size in aerosolised pathogen transmission: a review.

Jan Gralton, Euan Tovey, Mary-Louise McLaws, William D Rawlinson

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in The Journal of infection, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04454606 (The New Silicone N99 Half-Piece Respirator), which is not on this map. Cited by 293 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
293citing papers in PubMed, 5 pooled it
9.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04454606 nacompletednot on this mapstarted 2020, after this paper: background citation

The New Silicone N99 Half-Piece Respirator:VJR-NMU N99:New and Effective Tool to Prevent COVID-19

TypeinterventionalSponsorBangkok Metropolitan Administration Medical College and Vajira HospitalRan2020 to 2020Enrolled43ConditionsCOVID, Personal Protective EquipmentArmsFit test, Filtration Test
3 · Its place in the literature

Who cites it

293 citing papers in PubMed, 5 syntheses or guidelines pooled it, 696 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Airborne transmission of SARS-CoV-2 via aerosols.Reviews in medical virology · 2021
    Pooled it
  4. Pooled it
  5. Pooled it
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  9. Review
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  13. Review
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  15. Article
  16. Molecular Epidemiology ofMicroorganisms · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article

233 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jan GraltonSchool of Public Health and Community Medicine, The University of New South Wales, Australia.
Euan Tovey
Mary-Louise McLaws
William D Rawlinson
UNSW Sydney · AUPrince of Wales Hospital · AUWoolcock Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding respiratory pathogen transmission is essential for public health measures aimed at reducing pathogen spread. Particle generation and size are key determinant for pathogen carriage, aerosolisation, and transmission. Production of infectious respiratory particles is dependent on the type and frequency of respiratory activity, type and site of infection and pathogen load. Further, relative humidity, particle aggregation and mucus properties influence expelled particle size and subsequent transmission. Review of 26 studies reporting particle sizes generated from breathing, coughing, sneezing and talking showed healthy individuals generate particles between 0.01 and 500 μm, and individuals with infections produce particles between 0.05 and 500 μm. This indicates that expelled particles carrying pathogens do not exclusively disperse by airborne or droplet transmission but avail of both methods simultaneously and current dichotomous infection control precautions should be updated to include measures to contain both modes of aerosolised transmission.

Indexed as

Disease Transmission, InfectiousParticle SizeParticulate MatterAerosolsHumansHumidityMucusRespiratory Tract InfectionsAerosolsParticulate Matter

Identifiers

PMID21094184
PMCPMC7112663
OpenAlexW2061609002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.