ReviewThrombosis research2011
Platelet transfusions: impact on hemostasis, thrombosis, inflammation and clinical outcomes.
Review in Thrombosis research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Pulmonary thromboembolism in Glanzmann Thrombasthenia: a case report and systematic literature review.Annals of hematology · 2026Pooled it
- Tumor-mediated remote regulation of peripheral blood platelets.Cell biology and toxicology · 2025Review
- Apheresis platelets modulate myeloid dendritic cell immune responses.Scientific reports · 2025Article
- Storage duration of platelet concentrates and clinical outcomes in cardiac surgery patients.Transfusion · 2025Article
- Clinical characteristics & outcome of upper body deep vein thrombosis in critically ill patients.The Indian journal of medical research · 2025Observational
- Hip hemiarthroplasty versus closed reduction percutaneous pinning: A matched cohort analysis of 18,242 patients.Journal of orthopaedics · 2025Article
- Postoperative bleeding after dentoalveolar surgery in patients with thrombocytopenia-are prophylactic platelet transfusions necessary?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Initial Thrombocyte Concentrate Transfusion in Woman with Chronic Immune Thrombocytopenia Purpura (ITP) Who Underwent Mitral Valve Replacement Surgery: A Case Report.The American journal of case reports · 2023Article
- Stored whole blood transfusion initiates serum amyloid A activation monitored by real-time dynamic imaging.Blood transfusion = Trasfusione del sangue · 2023Article
- Preoperative mean platelet volume is a prognostic biomarker for survival in patients with gastric cancer: A cohort study.Medicine · 2022Article
- Role of Neurons and Glia Cells in Wound Healing as a Novel Perspective Considering Platelet as a Conventional Player.Molecular neurobiology · 2022Review
- Prognostic significance of the combination of preoperative red cell distribution width and platelet distribution width in patients with gastric cancer.BMC cancer · 2021Article
- Decreased mean platelet volume predicts poor prognosis in patients with pancreatic cancer.BMC surgery · 2021Article
- Theoretical and Experimental Optimization of the Graft Density of Functionalized Anti-Biofouling Surfaces by Cationic Brushes.Membranes · 2020Article
- Mean platelet volume and platelet distribution width serve as prognostic biomarkers in skull base chordoma: a retrospective study.BMC cancer · 2020Article
- Platelet Transfusion Practice and Related Outcomes in Pediatric Extracorporeal Membrane Oxygenation.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2020Article
- Mean platelet volume/platelet count ratio in colorectal cancer: a retrospective clinical study.BMC cancer · 2019Article
- Platelet Inflammatory Response to Stress.Frontiers in immunology · 2019Review
- Biomarker Profiling of Neurovascular Diseases in Patients with Stage 5 Chronic Kidney Disease.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis · 2018Article
- Towards increasing shelf life and haemostatic potency of stored platelet concentrates.Current opinion in hematology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Platelet transfusion is one of the most crucial therapeutic approaches in Medicine. However, severe and fatal adverse reactions may develop. In addition to their important function in hemostasis, platelets' role in inflammation has become more evident. Recently, platelets are also recognized as the main source of circulating soluble CD40 ligand (sCD40L, (CD154)), which plays significant roles in hemostasis, platelet activation, clot stability, interactions with other cells, and upregulation of different mediators. In this review, we will briefly highlight the importance of platelet transfusion, its role in inflammatory and thrombotic transfusion reactions, and visit the most recent findings on sCD40L.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.