Evidence map›Paper›PMID 21092937›Full record

ArticleBehaviour research and therapy2011

Maternal depressive history, teen 5HTTLPR genotype, and the processing of emotional faces: Exploring mechanisms of risk.

Rachel H Jacobs, Daniel S Pine, Michael E Schoeny, David B Henry, Jackie K Gollan, Gregory Moy, Edwin H Cook, Lauren S Wakschlag

Abstract readComparative Study
In one paragraph

Article in Behaviour research and therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Rachel H JacobsColumbia University, New York State Psychiatry Institute, New York, 10032, United States. jacobsr@childpsych.columbia.edu
Daniel S Pine
Michael E Schoeny
David B Henry
Jackie K Gollan
Gregory Moy
Edwin H Cook
Lauren S Wakschlag
Northwestern University · USUniversity of Illinois Chicago · USColumbia University · USNational Institute of Mental Health · USRoosevelt University · USUniversity of Chicago · US

Funding

Prenatal Smoking and Patterns of Youth Problem BehaviorR01DA015223 · NIDA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI WAKSCHLAG, LAUREN S · 2003 to 2007
$3.8M
NIDA NIH HHS DA15223NIDA NIH HHS R01 DA015223
6 · The paper itself

Abstract

Variations in the serotonin transporter gene (5HTTLPR) and biased processing of face-emotion displays both have been implicated in the transmission of depression risk, but little is known about developmental influences on these relationships. Within a community sample of adolescents, we examine whether 5HTTLPR genotype moderates the link between maternal depressive history and errors in face-emotion labeling. When controlling for current levels of depression and anxiety among youth, a two-way interaction between maternal depressive history and 5HTTLPR genotype was detected. Specifically, adolescents whose mothers reported a depressive history and who had a low expressing genotype made more errors in classifying emotional faces when compared with adolescents with an intermediate or high expressing genotype, with or without maternal depression history. These findings highlight the complex manner in which maternal depression and genetic risk may interact to predict individual differences in social information processing.

Indexed as

Facial ExpressionAdolescentAdolescent BehaviorAnxietyDepressionFamily HealthFemaleGenetic Predisposition to DiseaseGenetic VariationGenotypeHumansMaleMental ProcessesRisk FactorsSerotonin Plasma Membrane Transport ProteinsSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID21092937
PMCPMC3025079
OpenAlexW2011560658

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.