Evidence map›Paper›PMID 21088862›Full record

Trial reportLasers in medical science2011

Comparison between cold water immersion therapy (CWIT) and light emitting diode therapy (LEDT) in short-term skeletal muscle recovery after high-intensity exercise in athletes--preliminary results.

Ernesto Cesar Leal Junior, Vanessa de Godoi, José Luis Mancalossi, Rafael Paolo Rossi, Thiago De Marchi, Márcio Parente, Douglas Grosselli, Rafael Abeche Generosi, Maira Basso, Lucio Frigo and 3 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Lasers in medical science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06380179 (Assessing the Impact of Post-Exercise Photobiomodulation Application on Performance, Recovery, and Behavioral State in Trained Special Operator Population), which is not on this map. Cited by 55 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 10 pooled it
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06380179 nacompletednot on this mapstarted 2025, after this paper: background citation

Assessing the Impact of Post-Exercise Photobiomodulation Application on Performance, Recovery, and Behavioral State in Trained Special Operator Population

TypeinterventionalSponsorMusculoskeletal Injury Rehabilitation Research for Operational ReadinessRan2025 to 2026Enrolled29ConditionsPhotobiomodulation Therapy, Photomedicine, Low-Level Laser Therapy, Performance EnhancementArmsTHOR3 training + Photobiomodulation Therapy (PBMT), THOR3 training + sham PBMT
3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 10 syntheses or guidelines pooled it, 107 citations in OpenAlex.

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  16. Low-level laser therapy improves the VOLasers in medical science · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Ernesto Cesar Leal JuniorCenter for Research and Innovation in Laser, Nove de Julho University (UNINOVE), Rua Vergueiro, 235, 01504-001, São Paulo, SP, Brazil. ernesto.leal.junior@gmail.com
Vanessa de Godoi
José Luis Mancalossi
Rafael Paolo Rossi
Thiago De Marchi
Márcio Parente
Douglas Grosselli
Rafael Abeche Generosi
Maira Basso
Lucio Frigo
Shaiane Silva Tomazoni
Jan Magnus Bjordal
Rodrigo Alvaro Brandão Lopes-Martins
Universidade de Caxias do Sul · BRUniversidade de São Paulo · BRUniversidade Nove de Julho · BRUniversidade Cruzeiro do Sul · BRUniversidade Federal do Rio Grande do Sul · BRUniversity of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last years, phototherapy has becoming a promising tool to improve skeletal muscle recovery after exercise, however, it was not compared with other modalities commonly used with this aim. In the present study we compared the short-term effects of cold water immersion therapy (CWIT) and light emitting diode therapy (LEDT) with placebo LEDT on biochemical markers related to skeletal muscle recovery after high-intensity exercise. A randomized double-blind placebo-controlled crossover trial was performed with six male young futsal athletes. They were treated with CWIT (5°C of temperature [SD ±1°]), active LEDT (69 LEDs with wavelengths 660/850 nm, 10/30 mW of output power, 30 s of irradiation time per point, and 41.7 J of total energy irradiated per point, total of ten points irradiated) or an identical placebo LEDT 5 min after each of three Wingate cycle tests. Pre-exercise, post-exercise, and post-treatment measurements were taken of blood lactate levels, creatine kinase (CK) activity, and C-reactive protein (CRP) levels. There were no significant differences in the work performed during the three Wingate tests (p > 0.05). All biochemical parameters increased from baseline values (p < 0.05) after the three exercise tests, but only active LEDT decreased blood lactate levels (p = 0.0065) and CK activity (p = 0.0044) significantly after treatment. There were no significant differences in CRP values after treatments. We concluded that treating the leg muscles with LEDT 5 min after the Wingate cycle test seemed to inhibit the expected post-exercise increase in blood lactate levels and CK activity. This suggests that LEDT has better potential than 5 min of CWIT for improving short-term post-exercise recovery.

Indexed as

Adaptation, PhysiologicalAdolescentAdultAnalysis of VarianceC-Reactive ProteinCreatine KinaseCross-Over StudiesCryotherapyDouble-Blind MethodExerciseHumansImmersionLactic AcidLow-Level Light TherapyMaleMuscle FatigueC-Reactive ProteinCreatine KinaseLactic Acid

Identifiers

PMID21088862
PMCPMC3119799
OpenAlexW2114465147

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.